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For professionals in the pharmaceutical and fine chemical industries, understanding the specifications and applications of key intermediates is vital for efficient R&D and manufacturing. Ethyl 2,4-dichloro-3-oxobutyrate, with CAS number 88-00-6, stands out as a significant compound due to its versatile synthetic capabilities. This article delves into its core properties, essential uses, and provides guidance on procurement for discerning buyers.
The chemical structure of Ethyl 2,4-dichloro-3-oxobutyrate (C6H8Cl2O3) dictates its reactivity and broad applicability. Key properties often specified by manufacturers include its appearance, typically a white powder, and a minimum purity of 97%. Further technical data, such as its pKa of approximately 6.79, melting point ranging from 18-20 °C, and density around 1.315 g/cm³, are crucial for handling and process design. Its boiling point is noted at 118-120 °C at 15 Torr, indicating its thermal stability under specific conditions.
The primary applications for Ethyl 2,4-dichloro-3-oxobutyrate lie in its role as a reagent for organic synthesis and, more importantly, as a pharmaceutical intermediate. It is instrumental in the synthesis of various APIs, particularly serving as a precursor for Glp-1 receptor agonists. These advanced therapeutic agents are vital in managing conditions such as type 2 diabetes and obesity, highlighting the compound's significance in modern medicine. Researchers looking to buy this chemical often require it for developing new drug candidates or optimizing existing synthesis routes.
Procurement of Ethyl 2,4-dichloro-3-oxobutyrate involves identifying reputable manufacturers and suppliers who can guarantee consistent quality and competitive pricing. Buyers often search for 'Ethyl 2,4-dichloro-3-oxobutyrate price' or 'CAS 88-00-6 supplier' to identify potential partners. Engaging with manufacturers, especially those in China known for their large-scale production capabilities, can ensure a stable supply chain and cost efficiencies. When requesting a quote, detailing the required purity, quantity, and packaging is essential for obtaining accurate pricing and delivery terms.
In essence, Ethyl 2,4-dichloro-3-oxobutyrate is a cornerstone intermediate for critical pharmaceutical applications. By understanding its properties and engaging with reliable suppliers, researchers and manufacturers can ensure they have access to this indispensable compound, facilitating innovation and production in the pharmaceutical sector.
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