Ethyl 2-bromohexanoate (CAS 615-96-3) is a highly versatile organic compound recognized for its crucial role in advanced chemical synthesis and as a valuable pharmaceutical intermediate. This colorless liquid, also known by synonyms such as Ethyl 2-bromocapronate and 2-bromohexanoic acid ethyl ester, possesses a molecular formula of C8H15BrO2 and a molecular weight of approximately 223.11.

Key physical and chemical properties of Ethyl 2-bromohexanoate underscore its utility. It has a density of 1.221 g/mL at 25 °C, a boiling point ranging from 213-215 °C, and a melting point of 29 °C. The compound exhibits a flash point of 204 °F and an index of refraction of 1.45. Our stringent quality control measures ensure a purity of ≥99.0%, making it suitable for demanding applications in various industries. We prioritize the stability and integrity of our products, recommending that containers of Ethyl 2-bromohexanoate be kept tightly closed and stored in a cool, dry, well-ventilated area, away from incompatible substances, to maintain its superior quality over time.

The primary application of Ethyl 2-bromohexanoate lies in its function as a vital building block in the pharmaceutical industry. Its significance stems from its highly reactive bromine atom, which makes it an effective alkylating agent. In organic synthesis, this characteristic allows it to readily participate in the formation of new carbon-carbon bonds. Ethyl 2-bromohexanoate acts as an electrophile, facilitating reactions with various nucleophiles through substitution or addition mechanisms. This process is instrumental in introducing the ethyl 2-bromohexanoate moiety into diverse organic compounds, thereby enabling the creation of complex molecular structures that are foundational to the development of novel therapeutic agents.

Beyond its direct use as an intermediate, Ethyl 2-bromohexanoate has been extensively utilized in academic and industrial research for the synthesis of a wide array of specialized chemicals. For instance, it has been instrumental in studies involving lipophilic methotrexate conjugates, stannyl radical-mediated cleavage, and nickel-catalyzed arylation reactions. Its derivatives have shown promise as highly active PPARalpha agonists and gamma-secretase modulators, demonstrating its potential in areas related to metabolic and neurodegenerative diseases. Furthermore, it has contributed to the identification of dual inhibitors for 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1, and its structure has been explored in the context of haloalkane dehalogenases and novel thiazolone-benzenesulphonamide inhibitors of carbonic anhydrases. The compound's versatility also extends to the synthesis of angiotensin II receptor antagonists and cys-LT1 receptor antagonists, highlighting its broad applicability in medicinal chemistry.

As a leading manufacturer and supplier of high-quality chemical compounds, we are committed to providing Ethyl 2-bromohexanoate that meets the highest standards of purity and performance. Our extensive production capabilities and robust supply chain ensure consistent availability for your research and industrial needs. For detailed information regarding the price and to buy or purchase Ethyl 2-bromohexanoate, please reach out to our sales team. We offer flexible packaging options, including 25kg drums, and can accommodate specific customer requirements to ensure optimal delivery and handling. Our dedication to quality and customer satisfaction makes us a preferred partner for your chemical sourcing demands.