Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate (CAS: 503615-07-4) stands as a critical compound in modern pharmaceutical synthesis, particularly within the development of advanced anticoagulant medications. This sophisticated chemical entity, identified by its unique CAS Registry Number 503615-07-4, is extensively recognized for its vital role as both an intermediate and a reference impurity for Apixaban, a globally significant drug.

The chemical profile of this substance reveals a molecular formula of C22H22N4O4 and a molecular weight of 406.43 g/mol. Typically appearing as a white to off-white solid, its physical properties are well-defined. It possesses a melting point in the range of 150.6-152.3 °C and a predicted boiling point of approximately 651.6 ± 55.0 °C. The density is noted around 1.34 ± 0.1 g/cm3. In terms of solubility, it is slightly soluble in chloroform and DMF, which are important considerations for its handling and processing in pharmaceutical manufacturing. For optimal preservation, this compound should be stored in a cool, dark place under an inert atmosphere, ideally at temperatures below -20°C, to maintain its high purity and stability over time.

Its primary importance lies in its direct connection to Apixaban. Apixaban, marketed under various trade names, is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. This makes it an indispensable agent in the prevention and treatment of various thromboembolic disorders. Specifically, Apixaban is crucial for preventing venous thromboembolism following major orthopedic surgeries, such as total hip or knee replacement, and for preventing strokes in patients with non-valvular atrial fibrillation. The purity and structural integrity of intermediates like Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate are paramount to ensuring the safety, efficacy, and quality of the final Apixaban product. As a reference impurity, it is also indispensable for analytical testing and quality control processes in drug production, helping to identify and quantify any potential by-products or degradation products, thereby ensuring compliance with stringent pharmaceutical standards.

At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying high-quality pharmaceutical intermediates that meet the rigorous demands of the global drug development and manufacturing industry. Our commitment to excellence ensures that Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is produced with exceptional purity and consistency, making it a reliable choice for your research and production needs. We understand the critical nature of pharmaceutical raw materials and strive to provide products that facilitate seamless integration into complex synthesis pathways.

As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive prices for both bulk and smaller quantities of Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate. Whether you need to buy for research and development or for large-scale pharmaceutical purchase, we are equipped to meet your requirements with efficiency and professionalism. Our robust supply chain ensures timely delivery, and our technical support team is always ready to assist with any inquiries regarding product specifications or application. Contact us today to learn more about how we can support your pharmaceutical endeavors with our high-quality chemical solutions.