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In the realm of pharmaceutical innovation, specific chemical compounds often form the backbone of groundbreaking treatments. Exatecan Mesilate, identified by its CAS number 169869-90-3, stands out as a critical pharmaceutical chemical with profound implications for cancer therapy. As a potent topoisomerase I inhibitor, its precise mechanism of action and applications are of significant interest to researchers and clinicians alike. NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in making this essential compound accessible to the global market.
The chemical structure and properties of Exatecan Mesilate are finely tuned to disrupt the process of DNA replication within cancer cells. Topoisomerase I is an enzyme that regulates the topological state of DNA, facilitating processes like replication and transcription. By inhibiting this enzyme, Exatecan Mesilate causes an accumulation of DNA strand breaks, ultimately leading to cell cycle arrest and apoptosis. This targeted approach is particularly effective against rapidly proliferating cancer cells. The availability of Exatecan Mesilate powder in high purity is essential for ensuring the consistent efficacy of treatments derived from it. For those looking to buy Exatecan Mesilate, understanding its role as a topoisomerase I inhibitor is key.
One of the most exciting applications of Exatecan Mesilate lies in its use as a payload in antibody-drug conjugates (ADCs). ADCs are designed to deliver highly potent cytotoxic agents directly to cancer cells, a strategy that significantly enhances therapeutic efficacy while minimizing off-target toxicity. Exatecan Mesilate derivatives are frequently employed in these sophisticated drug delivery systems. The development of ADCs incorporating exatecan derivatives has shown remarkable success in treating various cancers, including those that are refractory to conventional chemotherapy. This advancement underscores the importance of securing a reliable supply of Exatecan Mesilate for the ongoing progress in targeted cancer therapies.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-grade Exatecan Mesilate, ensuring that the scientific community and pharmaceutical industry have access to a product that meets rigorous quality benchmarks. Our commitment to providing this vital cancer therapy drug facilitates research and development, allowing for the creation of more effective and safer treatments. By focusing on the needs of our clients and offering competitive pricing, we strive to be a leading supplier of pharmaceutical intermediates like Exatecan Mesilate, contributing to the global fight against cancer.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
