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Understanding the intricate chemical properties of key building blocks is fundamental for successful peptide synthesis and related research. Fmoc-Dab(Boc)-OH, scientifically identified as N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-t-butyloxycarbonyl-L-2,4-diaminobutyric acid, is a prime example of such a compound. Its structure and protected functional groups make it exceptionally versatile for advanced synthetic strategies.
The molecular structure of Fmoc-Dab(Boc)-OH features a 2,4-diaminobutyric acid backbone. The alpha-amino group is protected by the Fluorenylmethyloxycarbonyl (Fmoc) group, a common protecting group in peptide synthesis that is typically removed under mild basic conditions. Simultaneously, the gamma-amino group is protected by the tert-butyloxycarbonyl (Boc) group, which is acid-labile. This differential protection strategy, known as orthogonality, allows chemists to selectively manipulate each amino group at different stages of synthesis. For example, after coupling Fmoc-Dab(Boc)-OH into a growing peptide chain and removing the Fmoc group, the free gamma-amino group can be further modified before the Boc group is eventually cleaved during final deprotection.
Researchers aiming to buy Fmoc-Dab(Boc)-OH often require detailed technical specifications to ensure it meets their project's demands. NINGBO INNO PHARMCHEM CO.,LTD., a leading Fmoc-Dab(Boc)-OH manufacturer in China, provides these critical details, including molecular weight (440.5 g/mol), molecular formula (C24H28N2O6), and assurance of high purity, typically exceeding 98%. These specifications are crucial for anyone seeking high purity Fmoc-Dab(Boc)-OH for peptide synthesis.
The applications of Fmoc-Dab(Boc)-OH extend beyond standard peptide synthesis. It is frequently used in the creation of peptide-drug conjugates (PDCs), where the diaminobutyric acid residue serves as a linker for attaching therapeutic payloads. Its utility in solid-phase synthesis makes it a preferred choice for creating libraries of peptides for screening in drug discovery programs. As a trusted CAS 125238-99-5 supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent availability and quality for these advanced applications.
To procure this essential compound, consider NINGBO INNO PHARMCHEM CO.,LTD. We offer competitive Fmoc-Dab(Boc)-OH prices and are equipped to handle Fmoc-Dab(Boc)-OH bulk purchase inquiries. We invite researchers and procurement specialists to contact us for a quote and to discuss how our high-quality chemical reagents can support your scientific endeavors.
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A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
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