In the complex world of chemical synthesis, particularly for pharmaceutical applications, sourcing high-quality chiral intermediates is paramount. (S)-2-(9-Fluorenylmethoxycarbonyl)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid, identified by CAS number 136030-33-6 and often shortened to Fmoc-Tic-OH, is a critical amino acid derivative that plays a significant role in advanced organic synthesis, most notably in peptide chemistry.

For procurement professionals and research scientists, understanding the critical specifications of Fmoc-Tic-OH is the first step towards a successful acquisition. This compound typically appears as a white to off-white powder. Its key properties include a melting point of 146-149°C, a molecular formula of C25H21NO4, and a molecular weight of 399.44 g/mol. Crucially, its optical activity, often specified as [α]20/D +26.0±3.0° in methanol, confirms its specific (S) configuration, which is vital for applications demanding chiral purity.

When looking to buy this essential intermediate, many organizations consider manufacturers and suppliers in China due to the country's extensive capabilities in chemical production and competitive price structures. NINGBO INNO PHARMCHEM CO.,LTD. is a premier manufacturer and supplier based in China, specializing in providing high-purity Fmoc-Tic-OH and other advanced chemical intermediates. Our commitment is to ensure that every batch meets rigorous quality standards, typically exceeding 95% purity.

The primary application of Fmoc-Tic-OH is in Fmoc solid-phase peptide synthesis (SPPS), a standard technique for constructing peptides used in therapeutic drugs, diagnostic reagents, and scientific research. The incorporation of this unique tetrahydroisoquinoline derivative can impart specific conformational constraints or functionalities to the peptide backbone, influencing its biological activity and stability. The mild conditions required for Fmoc group removal are compatible with sensitive peptide structures.

For effective procurement, it’s essential to partner with a supplier that not only offers competitive pricing but also guarantees quality and reliability. When you choose to purchase (S)-2-(9-Fluorenylmethoxycarbonyl)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid from NINGBO INNO PHARMCHEM CO.,LTD., you benefit from our deep understanding of the pharmaceutical intermediate market, our robust quality control processes, and our efficient supply chain management.

In conclusion, securing high-quality Fmoc-Tic-OH is a strategic decision for any research-driven organization. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to being your trusted source from China, providing the expertise and high-purity chemical intermediates necessary to drive your projects forward with confidence.