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Exploring 1-Bromooctane: Properties, Synthesis, and Applications for R&D

For researchers and scientists engaged in discovery and development, having access to reliable, high-quality chemical building blocks is paramount. 1-Bromooctane (CAS: 111-83-1), a primary alkyl halide, serves as a versatile tool in numerous research and development projects. Its well-defined properties and reactivity make it a staple in organic synthesis laboratories worldwide. As a manufacturer and supplier specializing in fine chemicals, we aim to provide R&D professionals with the detailed information and product quality they need.

Key Properties for R&D Use

1-Bromooctane is characterized as a colorless to slightly yellow clear liquid. Its density of approximately 1.118 g/mL and a boiling point of around 201°C indicate its relative stability under standard laboratory conditions. The melting point of -55°C ensures it remains liquid even at cooler temperatures. A critical specification for R&D is its purity, typically ≥99.0% by Gas Chromatography (GC). Low moisture content (≤0.05%) and minimal non-volatile matter are also crucial, especially for reactions sensitive to water or impurities, such as Grignard reagent formation.

Synthesis Pathways for Research Laboratories

While industrial synthesis often focuses on scale and efficiency, understanding the core reactions is beneficial. The primary method involves reacting 1-octanol with hydrobromic acid. For laboratory-scale synthesis, researchers might employ variations of this method, using reagents like phosphorus tribromide (PBr3) or thionyl bromide (SOBr2) as alternatives for converting the alcohol to the bromide. Alternatively, direct esterification with HBr is common. Purification typically involves aqueous workup followed by distillation, although chromatography can be used for extremely high purity requirements in specialized research.

Applications in Research and Development

In the R&D environment, 1-Bromooctane is frequently used as an alkylating agent. It's employed to:

  • Synthesize novel organic molecules for drug discovery and material science.
  • Prepare organometallic reagents (e.g., Grignard reagents) for C-C bond formation.
  • Introduce lipophilic octyl chains to modify the properties of synthesized compounds, such as solubility or membrane permeability.
  • Develop new catalysts or ligands incorporating the octyl group.
  • Serve as a reference standard in analytical chemistry.

Its role in creating ethers, esters, and quaternary ammonium compounds makes it a versatile building block for exploring new chemical entities and advanced materials.

Sourcing for Your Lab

For research laboratories, securing a reliable supply of high-purity 1-Bromooctane is essential. When you need to buy 1-Bromooctane for your R&D projects, consider partnering with a reputable supplier known for quality and consistency. Our company provides 1-Bromooctane that meets rigorous specifications, ensuring predictable results in your experiments. We understand the needs of the research community and offer flexible quantities and competitive pricing. As a leading 1-Bromooctane manufacturer in China, we are committed to supporting your scientific endeavors.

If your research requires high-quality 1-Bromooctane, contact us to discuss your needs and obtain a quotation. We are dedicated to facilitating your scientific advancements with our reliable chemical intermediates.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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