In the dynamic world of chemical synthesis, certain compounds stand out for their versatility and critical role in diverse applications. One such compound is 1-Phenylpiperidine, an invaluable intermediate extensively utilized across various industries, particularly in organic synthesis and pharmaceuticals. Its unique chemical structure and reliable physical properties make it a cornerstone for developing new molecules and optimizing existing processes.
Chemically known as 1-Phenylpiperidine, or often by its synonyms such as N-PHENYLPIPERIDINE or Piperidine, 1-phenyl-, this compound carries the CAS.NO: 4096-20-2. Its molecular formula is C11H15N, resulting in a molecular weight of 161.24300. This precise chemical identity underscores its predictable behavior in reactions, which is paramount for its application in sensitive fields.
Understanding the physical and chemical properties of 1-Phenylpiperidine is crucial for its safe and effective handling. It presents as a white powder, indicative of its high purity and stability. Key properties include a density of 0.997 g/cm3, a boiling point of 258ºC at 760 mmHg, and a melting point around 41ºC. The relatively low melting point means it can be easily handled in its solid form at room temperature, yet melts readily for reactions requiring a liquid phase. Its flash point is 106.1ºC, signifying moderate flammability risks, while its refractive index of 1.544 provides further characterization. These consistent specifications are vital for chemists and researchers to ensure reproducible experimental results and product quality.
Quality assurance is paramount for 1-Phenylpiperidine, especially given its use in pharmaceutical applications. Reputable suppliers ensure strict adherence to specifications, guaranteeing a product with a purity of ≥98.0%. Critical quality parameters also include a moisture content typically below 0.25% and impurity levels not exceeding 0.3%. Such stringent quality controls are essential to prevent contamination and ensure the integrity of downstream products, making it a reliable raw material for complex synthesis pathways.
The primary applications of 1-Phenylpiperidine revolve around its function as an important raw material and intermediate in organic synthesis and the pharmaceutical industry. In organic synthesis, it serves as a versatile building block for creating a wide array of complex organic molecules, including those with potential biological activity. Its role in pharmaceuticals is particularly noteworthy, where it can be incorporated into the synthesis of active pharmaceutical ingredients (APIs) or used in the research and development of novel drug candidates. Its heterocyclic nature and the presence of a phenyl group offer unique reactivity profiles valuable in medicinal chemistry.
For optimal preservation and longevity, 1-Phenylpiperidine should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is also important to keep it away from incompatible substances to prevent degradation or hazardous reactions. Standard packaging often includes 25 kg drums, though flexible packaging options can typically be arranged to meet specific customer requirements.
When considering the acquisition of 1-Phenylpiperidine, finding a reliable manufacturer and supplier is critical. Quality consistency, purity, and competitive price are key factors that influence the decision to buy or purchase this compound. Leading suppliers understand the precise needs of their clients in the organic synthesis and pharmaceutical sectors, offering high-purity material backed by rigorous quality control. For those looking to source 1-Phenylpiperidine, engaging with established providers ensures both the integrity of the chemical and a streamlined procurement process, supporting continuous innovation and production in vital industries.
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