2-Iodophenol, identified by its CAS number 533-58-4, is a significant chemical compound in the realm of fine chemicals and intermediates. Known by synonyms such as o-Iodophenol or Adjacent Iodine Phenol, this versatile molecule presents a unique combination of an iodine substituent and a phenolic hydroxyl group on an aromatic ring. This ortho-substitution pattern is key to its reactivity and utility in numerous synthetic transformations. NINGBO INNO PHARMCHEM CO.,LTD. recognizes the importance of high-quality 2-Iodophenol in various industrial applications and offers this compound as a reliable raw material.

The physical characteristics of 2-Iodophenol CAS 533-58-4 are notable. It typically appears as light yellow to amber crystals. Its molecular formula is C6H5IO, resulting in a molecular weight of 220.01 g/mol. The melting point ranges from 42 to 45°C, and it boils between 186 and 188°C. With a density of 2.05 g/cm³, it is soluble in organic solvents like ethanol, ether, and aqueous sodium hydroxide solutions, though it shows insolubility in water. Proper storage is crucial for maintaining its stability, recommending storage in amber vials under a nitrogen atmosphere at a temperature of 2-8°C to prevent degradation, particularly oxidation.

The applications of 2-Iodophenol are diverse and span several critical industries. It is widely employed as a vital building block and intermediate in organic synthesis. One of its primary roles is in the pharmaceutical sector, where it serves in the synthesis of various active pharmaceutical ingredients (APIs). This includes intermediates for antibiotics and central nervous system (CNS) drugs. Its structure is amenable to various coupling reactions, such as Palladium-catalyzed cross-coupling reactions (like Suzuki, Sonogashira, Heck), which are fundamental in constructing complex molecular architectures relevant to drug discovery and manufacturing. The presence of the iodine atom provides a reactive site for these transformations, while the hydroxyl group can also be modified or participate in reactions, adding further versatility.

Beyond pharmaceuticals, 2-Iodophenol finds application in the agrochemical industry for the synthesis of pesticides and herbicides. Its reactivity allows for the creation of complex molecules with specific biological activities required for crop protection. In the field of material science, it is used as a precursor or modifier in the development of advanced materials. For instance, it can be incorporated into polymers to impart specific properties, such as improved flame retardancy or tailored interactions in epoxy resins. Furthermore, it has potential applications in the burgeoning field of organic electronics, including the synthesis of materials used in organic light-emitting diodes (OLEDs), where precise molecular structures are essential for performance.

The utility of 2-Iodophenol is significantly enhanced by its ability to form chelates and participate in regioselective reactions due to the proximity of the iodine and hydroxyl groups. This allows for controlled synthesis pathways, minimizing unwanted side products and improving reaction efficiency. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the 2-Iodophenol supplied meets rigorous quality standards, typically offering a purity of ≥98%. Each batch undergoes strict quality control testing, and a Certificate of Analysis (COA) is provided to confirm its specifications, including low heavy metal content, which is particularly important for sensitive applications like pharmaceuticals.

As a reliable manufacturer and supplier of fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 2-Iodophenol CAS 533-58-4 to meet global demand. We understand the critical nature of consistency and purity for our clients' manufacturing processes. We offer competitive price structures for bulk orders, catering to both research and industrial scale requirements. Customers looking to buy 2-Iodophenol can inquire about various packaging options, including drums and bags, tailored to different quantities and transport needs. We strive for efficient logistics and typically ensure dispatch within a few days after payment confirmation, facilitating timely delivery to our customers worldwide. To purchase or request a quote for 2-Iodophenol, or to discuss specific requirements, please contact us directly. Our team is ready to assist you with detailed product information and procurement processes. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for high-quality chemical raw materials.