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Exploring 2-Methoxy-5-(trifluoromethyl)benzonitrile: A Key Synthesis Intermediate

In the dynamic realm of chemical synthesis, certain compounds stand out for their pivotal roles in creating complex molecular structures. Among these is 2-Methoxy-5-(trifluoromethyl)benzonitrile, identified by its unique CAS number 34636-92-5. This versatile chemical intermediate is indispensable for a wide array of advanced chemical research and development endeavors, particularly within the specialized field of organic synthesis. Its distinct molecular composition, featuring both a methoxy and a trifluoromethyl group on a benzonitrile core, grants it specific reactivity and utility that are highly valued by chemists.


Understanding the fundamental physical and chemical properties of 2-Methoxy-5-(trifluoromethyl)benzonitrile is crucial for its effective application. It typically appears as a white powder, signifying its purity and stable solid form. Its molecular formula is C9H6F3NO, with a molecular weight of approximately 201.145 g/mol. Key physical parameters include a melting point ranging from 30 to 34 degrees Celsius, a boiling point estimated at 256.8 ± 40.0 degrees Celsius at 760 mmHg, and a density of 1.3 ± 0.1 g/cm3. The compound also exhibits a flash point of 109.1 ± 27.3 degrees Celsius and a vapor pressure of 0.0 ± 0.5 mmHg at 25 degrees Celsius, alongside an index of refraction of 1.464. These precise specifications underscore its consistent quality and suitability for demanding synthetic procedures.


The primary application of 2-Methoxy-5-(trifluoromethyl)benzonitrile lies in its role as an intermediate for organic synthesis. Its structure makes it an excellent building block for introducing specific functionalities into target molecules. The trifluoromethyl group, in particular, is known to impart unique properties such as increased metabolic stability and lipophilicity, making this compound especially valuable in the development of various chemical entities, including potential active pharmaceutical ingredients and agrochemicals. Researchers and manufacturers rely on such intermediates to create novel compounds with desired characteristics, pushing the boundaries of scientific innovation in numerous industries.


Quality assurance is paramount when sourcing chemical intermediates. NINGBO INNO PHARMCHEM CO.,LTD. ensures that 2-Methoxy-5-(trifluoromethyl)benzonitrile meets stringent specifications, with an assay typically at ≥98.0% purity. Proper handling and storage are also emphasized: the product is supplied in secure packaging, commonly in 25 kg drums, though custom packaging options are available to meet specific customer requirements. For optimal preservation of its integrity and efficacy, it is recommended to store this chemical in a cool, well-ventilated place, away from direct sunlight and moisture.


For those seeking a reliable manufacturer and supplier of high-quality 2-Methoxy-5-(trifluoromethyl)benzonitrile, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted source. Our commitment to excellence in production and rigorous quality control ensures that clients receive a product that consistently meets the highest industry standards. Whether you are looking to buy for research purposes or need to purchase in bulk for industrial applications, we offer competitive price options and efficient service. Our expertise in chemical synthesis and supply chain management positions us as a leading partner for your chemical sourcing needs, providing the essential intermediates required to drive your projects forward.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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