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Exploring the Applications of 4-Amino-3-fluorobenzoic Acid (CAS 455-87-8)

4-Amino-3-fluorobenzoic acid, identified by its CAS number 455-87-8, stands as a pivotal chemical compound in the realm of organic synthesis. Known also by synonyms such as 3-fluoro-4-aminobenzoic acid, this versatile molecule is a crucial building block for developing various advanced chemical products. NINGBO INNO PHARMCHEM CO.,LTD. specializes in the production and supply of high-purity 4-Amino-3-fluorobenzoic acid, catering to diverse industrial and research requirements.


The distinct physical and chemical properties of 4-Amino-3-fluorobenzoic acid underpin its wide applicability. It typically appears as white to light yellow crystals, signaling its purity and stability. With a molecular formula of C7H6FNO2 and a molecular weight of approximately 155.13 g/mol, it possesses a precise chemical structure. Key physical indicators include a melting point ranging from 215 to 218°C, a boiling point of about 320.8°C at 760 mmHg, and a flash point of approximately 147.8°C. Its density is around 1.4 g/cm3, and it exhibits a low vapor pressure of 0.0 mmHg at 25°C, coupled with an index of refraction of 1.606. These parameters ensure its consistent performance and reliability in complex chemical reactions.


At its core, 4-Amino-3-fluorobenzoic acid serves as an indispensable intermediate in various organic synthesis pathways. Its unique molecular structure, featuring both an amino group and a carboxylic acid group, alongside a fluorine atom, makes it highly reactive and versatile. This allows for its integration into the synthesis of a broad spectrum of organic compounds, including pharmaceuticals, agrochemicals, and specialized fine chemicals. Researchers and manufacturers rely on its consistent quality for creating novel molecular structures and improving existing chemical processes.


Beyond general organic synthesis, recent findings highlight the significant biochemical implications of 4-Amino-3-fluorobenzoic acid. Studies indicate that it acts as an inhibitor of the enzyme nitric oxide synthase (NOS). Nitric oxide is a critical signaling molecule involved in numerous physiological processes, including blood pressure regulation, immune response, and neurotransmission. By competitively inhibiting NOS, 4-Amino-3-fluorobenzoic acid can modulate the production of nitric oxide from L-arginine. This mechanism has shown promise in mitigating chronic inflammation, partly by reducing blood pressure and inhibiting the generation of reactive oxygen species that can cause cellular damage. Its potential to induce hyperpolarization of the cell membrane also suggests therapeutic benefits for certain conditions, opening avenues for its application in advanced pharmacological research and development.


NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing 4-Amino-3-fluorobenzoic acid of the highest quality. Each batch undergoes rigorous testing to meet stringent specifications, guaranteeing an assay purity of ≥98.0%. This commitment to quality ensures optimal performance and reliability for critical applications. For packaging, the product is typically supplied in 25 kg drums, ensuring safe transport and long-term stability. Furthermore, custom packaging solutions are available to meet specific customer requirements, demonstrating flexibility and dedication to client satisfaction. Proper storage in a cool, ventilated place is recommended to maintain the product's integrity over time.


For those looking to buy or purchase high-quality 4-Amino-3-fluorobenzoic acid, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable manufacturer and supplier. We pride ourselves on offering competitive price options for both small-scale research quantities and large-volume industrial orders. Our extensive expertise in chemical synthesis and robust supply chain ensures timely delivery and consistent product availability. We invite potential partners and clients to inquire about our product specifications and current price lists. Partnering with a trusted manufacturer ensures access to premium raw materials essential for successful innovation and production in various chemical industries.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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