2-(4-Pyridinylphenyl)acetonitrile (CAS: 112170-33-9) is a compound that has garnered increasing attention in the scientific community due to its versatile chemical properties and its role as a key intermediate in various synthesis pathways. As a reputable manufacturer and supplier, we often receive inquiries about its specific characteristics, which are crucial for researchers and formulators planning their experiments and production processes. Understanding these properties is the first step for anyone looking to buy this valuable chemical.

At its core, 2-(4-Pyridinylphenyl)acetonitrile is an organic compound featuring a pyridine ring linked to a phenylacetonitrile group. This structural arrangement imbues it with a dual nature: the basicity of the pyridine nitrogen and the electrophilic potential of the nitrile carbon. The pyridine ring can participate in coordination chemistry or undergo electrophilic aromatic substitution under specific conditions. Meanwhile, the nitrile group (-CN) is a highly versatile functional group, capable of undergoing hydrolysis to carboxylic acids, reduction to amines, or nucleophilic addition reactions. This inherent reactivity makes it an excellent building block for synthesizing more complex molecules.

One of the most critical aspects for industrial applications is stability. Our product, 2-(4-Pyridinylphenyl)acetonitrile, is generally stable under normal temperature and pressure conditions. This characteristic is vital for storage, transportation, and integration into multi-step synthesis where intermediates need to retain their integrity over time. We recommend storing it in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances. This ensures that when you purchase from us, you receive a product that performs reliably in your laboratory or production facility.

The acidity factor (pKa) is also an important consideration for chemists, and for 2-(4-Pyridinylphenyl)acetonitrile, it's approximately 5.35 ± 0.10 (predicted). This indicates a weakly acidic character for the alpha-hydrogens adjacent to the nitrile group, allowing for deprotonation by strong bases to form a carbanion. This carbanion can then act as a nucleophile in various carbon-carbon bond-forming reactions, such as alkylations or Michael additions. This reactivity is fundamental to its use as an intermediate in creating more elaborate organic structures, a key reason why many seek to buy it from reliable manufacturers.

Furthermore, its physical appearance as a white powder is a common visual indicator of purity for many fine chemicals. The melting point of 116-117.5 °C is also a critical parameter for identification and quality assessment. For those looking for a dependable supplier, clarity on these physical and chemical properties, alongside a guaranteed purity of 97%+, is essential. We are committed to providing comprehensive technical data to support your research and procurement decisions, ensuring you get the most out of this exceptional organic synthesis intermediate.