Alpha Lipoic Acid, often abbreviated as ALA, is a naturally occurring compound that plays a vital role in cellular metabolism. As a key API (Active Pharmaceutical Ingredient) and nutritional ingredient, Alpha Lipoic Acid CAS 1077-28-7 is highly valued for its unique chemical properties and broad spectrum of biological activities. At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing high-purity Alpha Lipoic Acid in powder form, meeting stringent pharmaceutical and nutraceutical standards.
Chemically, Alpha Lipoic Acid is an organosulfur compound derived from caprylic acid. It is a disulfide, and its reduced form is dihydrolipoic acid. This redox pair is crucial for its function as a cofactor for mitochondrial enzymes involved in energy production, such as the pyruvate dehydrogenase complex and the alpha-ketoglutarate dehydrogenase complex. These enzyme systems are central to the Krebs cycle, the primary pathway for generating ATP, the cell's energy currency.
One of the most significant properties of Alpha Lipoic Acid is its potent antioxidant capability. Unlike many other antioxidants, ALA is unique because it is amphipathic, meaning it is soluble in both water and fat. This allows it to function in various cellular environments, including cell membranes and aqueous compartments within the cell. This broad solubility enables ALA to scavenge free radicals throughout the body, protecting cells from oxidative stress, which is implicated in numerous chronic diseases and the aging process.
Beyond directly neutralizing reactive oxygen and nitrogen species, Alpha Lipoic Acid also supports the body's endogenous antioxidant defense system. It can regenerate other important antioxidants, such as Vitamin C, Vitamin E, and glutathione, from their oxidized forms. By recycling these vital compounds, ALA helps to maintain a robust antioxidant network within the body, enhancing overall cellular protection.
The therapeutic potential of Alpha Lipoic Acid has been extensively studied, particularly in the context of metabolic disorders. A prominent application is in the management of diabetic complications, specifically diabetic neuropathy. Diabetic neuropathy is a common and often debilitating condition characterized by nerve damage caused by prolonged high blood sugar levels. Oxidative stress and impaired energy metabolism are believed to be key contributors to this nerve damage. Clinical studies have shown that Alpha Lipoic Acid supplementation can improve symptoms of diabetic neuropathy, such as pain, burning, numbness, and tingling, by reducing oxidative stress and potentially improving nerve blood flow and function.
Furthermore, Alpha Lipoic Acid's role in glucose metabolism is also of interest. It has been shown to improve insulin sensitivity, helping cells take up glucose more efficiently. This effect can contribute to better blood sugar control, which is crucial for preventing or slowing the progression of diabetic complications, including cardiovascular issues. While the primary benefit in the source material highlighted diabetic neuropathy and cardiovascular disease, ALA's metabolic actions underscore its potential broader utility in supporting metabolic health.
As a raw material, the quality and purity of Alpha Lipoic Acid are paramount, especially for pharmaceutical and nutraceutical applications where it will be incorporated into final dosage forms or supplements consumed by patients. High-quality ALA powder, typically slightly yellow and crystalline, must meet strict specifications for identity, purity, physical characteristics like melting point and particle size, as well as limits for impurities, residual solvents, and microbial contamination. Adherence to standards like USP ensures that the material is safe and efficacious for its intended use.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying Alpha Lipoic Acid CAS 1077-28-7 that adheres to the highest quality benchmarks. Our manufacturing processes are designed to ensure exceptional purity, consistency, and reliability. We understand the critical requirements of the pharmaceutical and supplement industries and are committed to providing material that meets or exceeds international pharmacological standards.
For companies seeking a trustworthy manufacturer and reliable supplier of Alpha Lipoic Acid API, NINGBO INNO PHARMCHEM CO.,LTD. is a partner you can depend on. We maintain robust quality control systems at every stage of production to guarantee that our Alpha Lipoic Acid powder is of superior quality.
Inquiries regarding the current price of Alpha Lipoic Acid are always welcome. We strive to offer competitive price structures for bulk purchase, ensuring our customers receive excellent value without compromising on quality. Whether you are looking to buy a sample for testing or arrange a large-scale purchase, our team is ready to assist you with detailed product information, specifications, and pricing.
Choosing the right supplier is critical for maintaining the integrity and efficacy of your final products. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a leading manufacturer in the field, providing not just a product, but a promise of quality and reliability. Our comprehensive support ensures a smooth purchase experience from initial inquiry to final delivery. We invite potential customers to discuss their requirements and learn more about how we can serve as their preferred supplier for high-quality Alpha Lipoic Acid.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
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