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Exploring the Synthesis and Applications of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

The intricate world of chemical synthesis is driven by the discovery and application of versatile intermediates. NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine (CAS: 90213-66-4), a compound that plays a pivotal role in the pharmaceutical industry. Its unique chemical structure and reactivity make it an indispensable building block for a range of complex molecules, with its most prominent application being the synthesis of Tofacitinib citrate.

Understanding the chemical properties of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine is crucial for its effective utilization. With the molecular formula C6H3Cl2N3 and a molecular weight of 188.01400, this compound exhibits a melting point of 247-250°C and a boiling point of 312°C. These thermal properties indicate good stability, which is essential for handling and reaction processes in pharmaceutical manufacturing. The compound is typically supplied as an off-white to yellow solid, emphasizing the need for precise synthesis and quality control to maintain its intended reactivity.

The significance of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine as an intermediate cannot be overstated. As a key component in the Tofacitinib citrate synthesis, it directly contributes to the production of a vital medication for patients suffering from autoimmune disorders. The compound's structure, a dichlorinated pyrrolo-pyrimidine ring, provides a reactive scaffold that chemists can manipulate to build the complex molecular architecture of Tofacitinib. This highlights the importance of reliable chemical synthesis for producing such critical components.

NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-purity organic synthesis building blocks, including 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine. Our commitment to quality ensures that manufacturers can depend on our products for consistent results in their production lines. We understand the demanding requirements of the pharmaceutical sector and strive to meet and exceed them through rigorous quality assurance protocols. Sourcing high-grade intermediates is a cornerstone of successful drug discovery and development.

The application scope of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine extends beyond its primary use. Researchers are continually exploring its potential in synthesizing other novel bioactive compounds, leveraging its heterocyclic nature for innovative chemical exploration. This adaptability makes it a sought-after material in academic and industrial research laboratories. The efficiency of pyrrolo-pyrimidine synthesis pathways is a constant area of focus for improving yields and reducing costs.

As a forward-thinking chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the pharmaceutical industry's advancements. Our expertise in producing and supplying essential intermediates like 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine reaffirms our commitment to facilitating breakthroughs in medicine. By providing reliable access to these crucial materials, we aim to empower researchers and manufacturers in their pursuit of novel treatments and improved healthcare outcomes.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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