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Propionic acid, also known as propanoic acid (CAS 79-09-4), is not only an industrial chemical but also a compound with significant biological relevance. It is naturally produced in the human body as a byproduct of the metabolic breakdown of certain fatty acids and amino acids. Furthermore, propionic acid is a key metabolite produced by the gut microbiota, particularly through the fermentation of dietary fiber. These short-chain fatty acids (SCFAs) are crucial for maintaining gut health and play roles in host metabolism and immune function. The presence of propionic acid in human metabolism and its production by gut microbes highlight its natural occurrence.
In the realm of bacteriology, specific bacteria, notably Propionibacteria such as Cutibacterium acnes, produce propionic acid. This bacterium is commonly found on human skin and is associated with acne. The metabolic activity of propionic acid bacteria is also responsible for characteristic flavors and textures in certain cheeses, such as Emmental. The biotechnological propionic acid synthesis often utilizes these microbial pathways, demonstrating how biological processes can be harnessed for industrial production. The understanding of propionic acid occurrence in bacteria is central to these biotechnological efforts.
Propionic acid is also involved in energy metabolism, being converted to succinyl-CoA, an intermediate in the citric acid cycle. However, imbalances in its metabolism can lead to disorders like propionic acidemia. The influence of gut microbiota-derived propionate on brain function and behavior is an active area of research, with potential implications for understanding neurological conditions. When considering the chemical production of propionic acid or its industrial uses, it's important to recognize its deep connection to biological systems. The safety of propionic acid handling remains critical, even when discussing its biological roles, due to its inherent chemical hazards.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
