In the realm of fine chemicals, understanding the intricate properties and application potential of key intermediates is paramount. 2-Bromo-3-Chloro-5-(Trifluoromethyl)Pyridine, bearing the CAS number 75806-84-7, is a compound that exemplifies this importance. Available from NINGBO INNO PHARMCHEM CO.,LTD., this molecule is a clear, colorless liquid, characterized by a high assay purity of ≥99.0%. Its physical and chemical attributes make it a highly versatile tool for chemists across various disciplines, from organic synthesis to the development of specialized materials.

The chemical structure of 2-Bromo-3-Chloro-5-(Trifluoromethyl)Pyridine is its most defining feature. The pyridine core, a six-membered heterocyclic aromatic ring containing one nitrogen atom, is substituted with three distinct functional groups: a bromine atom at the 2-position, a chlorine atom at the 3-position, and a trifluoromethyl (CF3) group at the 5-position. This specific halogenation pattern, coupled with the electron-withdrawing nature of the CF3 group, significantly influences the compound's reactivity. The bromine atom, being a good leaving group, is particularly amenable to various substitution and cross-coupling reactions, such as the Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling. These reactions are fundamental for building carbon-carbon bonds and are extensively used in constructing complex organic frameworks.

The physical properties of 2-Bromo-3-Chloro-5-(Trifluoromethyl)Pyridine, such as its density (1.8±0.1 g/cm3) and boiling point (226.9±35.0 °C at 760 mmHg), provide crucial data for handling and process design. Its flash point of 91.0±25.9 °C also dictates safety protocols in laboratory and industrial settings. These parameters ensure that the compound can be safely stored and utilized in various reaction conditions, contributing to its wide adoption. For those seeking a reliable source for this chemical, NINGBO INNO PHARMCHEM CO.,LTD. offers a product that meets rigorous quality specifications, ensuring predictability in experimental outcomes.

The applications of 2-Bromo-3-Chloro-5-(Trifluoromethyl)Pyridine extend beyond traditional organic synthesis. Its unique electronic and steric properties, imparted by the trifluoromethyl group and halogen substituents, make it a candidate for use in material science. For example, substituted pyridines can be incorporated into polymers to modify their thermal, optical, or electronic properties. Researchers might explore its use in the development of functional dyes, organic semiconductors, or advanced coatings. The ability to perform selective functionalization at the bromine site allows for the precise integration of this pyridine moiety into larger molecular systems or polymeric chains.

Understanding the full spectrum of chemical reactions that 2-Bromo-3-Chloro-5-(Trifluoromethyl)Pyridine can participate in is key to unlocking its full potential. Its role as an intermediate in synthesizing bioactive molecules for pharmaceuticals and agrochemicals is well-established, but its utility in creating novel materials is an area of growing interest. Sourcing this compound from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers and developers have access to a consistent, high-quality product that can drive innovation across multiple scientific frontiers.