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At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in the production of high-quality pharmaceutical intermediates, and 8-Bromo-3-methyl-xanthine (CAS 93703-24-3) stands out for its critical role in advanced pharmaceutical synthesis. This compound, a substituted derivative of xanthine, possesses unique chemical properties that make it an invaluable building block in medicinal chemistry.
The synthesis of 8-Bromo-3-methyl-xanthine typically involves the bromination of 3-methylxanthine. This reaction requires careful control of conditions, often utilizing agents like bromine or N-bromosuccinimide (NBS) in suitable solvents such as acetic acid. The process is designed to selectively introduce a bromine atom at the 8th position of the purine ring, a modification crucial for its subsequent use in drug development. The resulting product is characterized by its light yellow to white powder appearance and a high melting point, typically around 300°C, indicating its stability.
The primary application of 8-Bromo-3-methyl-xanthine is as a key intermediate in the synthesis of Linagliptin. Linagliptin is a highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor used extensively in the treatment of type 2 diabetes. The molecular structure of 8-Bromo-3-methyl-xanthine provides the necessary foundation for the complex chemical transformations required to produce Linagliptin, ensuring the drug's efficacy and therapeutic profile. This linkage underscores the importance of reliable sourcing for this critical intermediate.
Furthermore, research has indicated potential applications for 8-Bromo-3-methyl-xanthine in the development of other therapeutic agents, including antiviral and anti-tumor drugs. Its structure as a purine derivative allows for exploration in various biochemical pathways and enzyme inhibition studies. As a leading 8-Bromo-3-methyl-xanthine manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting these diverse research and development efforts by ensuring a consistent supply of premium-grade material.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to advancing pharmaceutical innovation through the supply of high-quality intermediates. Our comprehensive understanding of the chemical synthesis and rigorous quality assurance processes for 8-Bromo-3-methyl-xanthine guarantee that our clients receive a product that meets the most demanding specifications. We invite you to partner with us for your pharmaceutical intermediate needs and experience the difference that quality and reliability can make.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
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