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The landscape of cancer treatment is continuously evolving, driven by a deeper understanding of cellular mechanisms and the development of novel therapeutic agents. Within this sphere, 10-Hydroxycamptothecin (CAS 19685-09-7) has emerged as a compound of significant interest due to its potent activity as a topoisomerase I inhibitor. As a derivative of camptothecin, it inherits a legacy of anti-cancer potential, refined through chemical synthesis to enhance its therapeutic profile.
The primary mechanism by which 10-Hydroxycamptothecin exerts its anti-tumor effects is through its interaction with DNA topoisomerase I. This crucial enzyme plays a vital role in managing DNA supercoiling during replication and transcription. By stabilizing the transient DNA-topoisomerase I cleavage complex, 10-Hydroxycamptothecin effectively traps the enzyme, leading to the formation of irreversible DNA double-strand breaks. This ultimately triggers cell cycle arrest and apoptosis in rapidly dividing cancer cells. For researchers aiming to explore these mechanisms, sourcing reliable compounds is key. Many seek to buy 10-hydroxycamptothecin from established 10-hydroxycamptothecin suppliers in China known for quality.
The therapeutic potential of 10-Hydroxycamptothecin is being actively investigated across a spectrum of cancers. Its efficacy has been demonstrated in preclinical models for conditions such as hepatoma, leukemia, and various solid tumors. Its role extends beyond direct therapeutic application; it serves as a critical pharmaceutical intermediate for the synthesis of next-generation camptothecin analogs and combination therapies. Understanding the price of 10-hydroxycamptothecin for research from a trusted manufacturer of 10-hydroxycamptothecin CAS 19685-09-7 is an important step for research institutions planning extensive studies.
Advancing cancer research often hinges on access to high-quality chemical building blocks. When planning to order high purity hydroxycamptothecin, collaboration with a dedicated manufacturer ensures product integrity and supply security. This allows researchers to focus on the scientific endeavor, confident in the reliability of their materials. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing the global research community with superior 10-Hydroxycamptothecin, supporting the development of innovative cancer treatments. We welcome inquiries to discuss bulk purchase options and how our products can contribute to your research breakthroughs.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
