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Exploring the Utility of N,N'-Di-tert-butoxycarbonyl-L-histidine in Chemical Research

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting chemical research by providing high-quality, specialized chemical intermediates. N,N'-Di-tert-butoxycarbonyl-L-histidine (CAS 20866-46-0) is a versatile compound that finds extensive use across various branches of chemical research, particularly in organic synthesis and biochemistry. Its unique structure and protective groups make it an invaluable asset for chemists undertaking complex synthetic challenges.

The primary utility of N,N'-Di-tert-butoxycarbonyl-L-histidine lies in its role as a protected form of the amino acid histidine. Histidine is known for its imidazole ring, which can participate in acid-base catalysis and metal coordination. In synthetic chemistry, the tert-butoxycarbonyl (Boc) protecting groups on both the alpha-amino and imidazole nitrogen atoms provide a stable shield, allowing for controlled reactions elsewhere in a molecule or enabling the selective deprotection and functionalization of the histidine moiety. This dual protection is crucial for preventing unwanted side reactions and ensuring regioselectivity during multi-step syntheses.

Researchers in areas such as medicinal chemistry, materials science, and biochemical studies frequently utilize this compound. For instance, in the synthesis of modified peptides or peptidomimetics, N,N'-Di-tert-butoxycarbonyl-L-histidine is employed to introduce the histidine residue with specific modifications or linkages. Its solubility in common organic solvents also facilitates its integration into various reaction systems. The consistent high purity offered by NINGBO INNO PHARMCHEM CO.,LTD. ensures that experimental results are reliable and reproducible, which is fundamental to scientific progress.

As a key building block, N,N'-Di-tert-butoxycarbonyl-L-histidine empowers chemists to explore novel molecular architectures and functionalities. Its availability from NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers have access to a dependable source for their critical research needs. We are committed to facilitating scientific discovery by providing the essential chemical tools that enable groundbreaking research and development.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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