While commonly recognized for its bronchodilatory effects in treating conditions like asthma and bronchitis, Theophylline (CAS 58-55-9) possesses a spectrum of complex pharmacological actions that extend beyond simple airway relaxation. A deeper dive into its mechanism of action reveals its influence on intracellular signaling pathways and its potential as a modulator of inflammation. Understanding these multifaceted properties is crucial for appreciating its full therapeutic and research value. As a vital pharmaceutical intermediate, sourcing high-quality Theophylline from reputable suppliers in China is essential for robust scientific inquiry.

At its core, Theophylline functions as a non-selective inhibitor of phosphodiesterase (PDE) enzymes. These enzymes are responsible for breaking down cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). By inhibiting PDE, Theophylline leads to increased intracellular levels of cAMP, which promotes the relaxation of smooth muscles, including those in the bronchial tubes. This explains its effectiveness in combating bronchoconstriction. This critical mechanism is a focal point for research into respiratory diseases, and knowledge of Theophylline CAS 58-55-9 uses is vital for researchers.

Furthermore, Theophylline has been observed to stimulate the respiratory drive at the central nervous system (CNS) level. It acts on the medullary respiratory centers, enhancing breathing efforts, which is particularly relevant in cases of respiratory depression. This action has led to its consideration in managing conditions like apnea in preterm infants, although newer agents often offer a better safety profile. The comparison between Theophylline and caffeine for apnea treatment highlights these nuances.

Beyond its effects on muscle and breathing, Theophylline is also investigated for its anti-inflammatory properties. It can modulate the activity of immune cells, such as eosinophils and neutrophils, which play a significant role in the inflammatory cascade of diseases like asthma and COPD. Research into these anti-inflammatory pathways continues to uncover potential new therapeutic applications for Theophylline or its derivatives.

For those looking to buy Theophylline, understanding these varied actions is key. Whether for direct therapeutic use, as a reference compound in research, or as a crucial pharmaceutical intermediate, the quality of Theophylline sourced from China manufacturers is paramount. The price of Theophylline should be considered alongside its purity and source reliability.

In summary, Theophylline is far more than just a bronchodilator. Its capacity to inhibit phosphodiesterase, stimulate the respiratory drive, and potentially exert anti-inflammatory effects makes it a compound of enduring interest in pharmacology and medicine. Its availability from reliable Chinese suppliers ensures continued progress in both clinical practice and scientific discovery.