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In the dynamic world of fine chemicals and pharmaceutical synthesis, understanding the properties and applications of key compounds is vital for innovation. Methyl 6-Fluoro-1H-indole-4-carboxylate, bearing the CAS number 1082040-43-4, is one such compound that has garnered significant attention. Its utility as a versatile building block makes it indispensable for researchers and manufacturers in the life sciences sector.
Understanding the Compound: Methyl 6-Fluoro-1H-indole-4-carboxylate
This compound is characterized by its unique molecular structure, which includes a fluorinated indole ring and a methyl ester group. With the molecular formula C10H8FNO2 and a molecular weight of approximately 193.17 g/mol, it presents specific reactivity that is highly valuable in organic synthesis. Its appearance as a light yellow to yellow solid further aids in its identification and handling in laboratory settings.
Applications in Pharmaceutical Development
The primary application driving the demand for Methyl 6-Fluoro-1H-indole-4-carboxylate is its role as an intermediate in the synthesis of Rucaparib. Rucaparib is a crucial PARP (Poly ADP-ribose polymerase) inhibitor, a class of drugs that have shown significant promise in treating cancers with specific genetic mutations, such as BRCA mutations. By inhibiting PARP enzymes, these drugs can enhance the effectiveness of DNA damage repair mechanisms in cancer cells, leading to their demise. Therefore, the consistent availability of high-quality Methyl 6-Fluoro-1H-indole-4-carboxylate is directly linked to the production of these life-saving oncology drugs.
Sourcing Strategy for Buyers
For procurement managers and research scientists looking to buy Methyl 6-Fluoro-1H-indole-4-carboxylate, partnering with reliable manufacturers is key. We, as a dedicated producer, ensure stringent quality control and offer this fine chemical at competitive prices. Our manufacturing capabilities allow us to cater to both small-scale R&D needs and larger bulk production orders. To discuss pricing, purity specifications, and delivery options, we encourage you to reach out for a quotation. Ensuring a stable supply of this critical intermediate is paramount for advancing pharmaceutical research and bringing new treatments to market.
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