Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
The pharmaceutical industry is increasingly leveraging peptide-based therapeutics due to their high specificity, potency, and lower immunogenicity compared to traditional small-molecule drugs. At the heart of synthesizing these complex molecules lies the availability of high-quality building blocks, such as Fmoc-Arg(Pbf)-OH (CAS: 154445-77-9). As a dedicated manufacturer and supplier of advanced chemical intermediates, we are committed to facilitating breakthroughs in drug discovery by providing essential reagents like Fmoc-Arg(Pbf)-OH.
The Synthesis and Chemical Properties of Fmoc-Arg(Pbf)-OH
Fmoc-Arg(Pbf)-OH is a chemically modified form of the amino acid arginine, featuring the Fmoc group for N-terminal protection and the Pbf group for side-chain protection. The Pbf group is critical for preventing unwanted reactions at the guanidino group of arginine during peptide synthesis. Its chemical structure, C34H40N4O7S, with a molecular weight of 648.77, is designed for optimal performance in Solid Phase Peptide Synthesis (SPPS).
The synthesis of Fmoc-Arg(Pbf)-OH involves the protection of the alpha-amino group of arginine with the Fmoc moiety and the subsequent protection of the side-chain guanidino group with the Pbf sulfonyl group. The Pbf group's key advantage lies in its facile removal using trifluoroacetic acid (TFA), a common reagent in peptide deprotection protocols. This characteristic makes it an efficient and preferred choice for many peptide synthesis workflows, allowing researchers to buy Fmoc-Arg(Pbf)-OH with confidence.
Applications in Drug Discovery and Development
Fmoc-Arg(Pbf)-OH is indispensable in the synthesis of a wide range of peptide-based drugs and research compounds. Its inclusion in peptide sequences can enhance stability, improve receptor binding, and modulate biological activity. Specifically, it is used in:
Researchers seeking to purchase Fmoc-Arg(Pbf)-OH often do so for its proven utility in creating peptides with specific pharmacological profiles. As a leading Fmoc-Arg(Pbf)-OH supplier in China, we understand the critical role this reagent plays in accelerating drug discovery pipelines.
Procurement and Quality Assurance
When sourcing critical research materials, partnering with a reliable Fmoc-Arg(Pbf)-OH manufacturer is paramount. We ensure that our product meets stringent purity standards (typically ≥99%), which is vital for the success of complex synthesis and downstream pharmaceutical applications. Our commitment to quality control means you can always trust the consistency and performance of our reagents, allowing you to focus on innovation rather than material variability.
We offer competitive Fmoc-Arg(Pbf)-OH price points to support research and development efforts globally. If you are looking to buy Fmoc-Arg(Pbf)-OH, consider our services for high-purity materials, reliable supply, and excellent technical support. Contact us today to discuss your peptide synthesis needs and obtain a quote.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
