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FMOC-L-Valine (CAS 68858-20-8): Essential Intermediate for Pharmaceutical Synthesis

NINGBO INNO PHARMCHEM CO.,LTD. is pleased to highlight the significance of FMOC-L-Valine (CAS: 68858-20-8), a crucial pharmaceutical intermediate essential for advancements in drug development. As a high-purity amino acid derivative, FMOC-L-Valine plays an indispensable role in various synthetic processes, particularly in the production of complex pharmaceutical compounds and peptides.


FMOC-L-Valine, chemically known as N-alpha-Fmoc-L-Valine, is characterized by its white powder appearance. It boasts a molecular formula of C20H21NO4 and a molecular weight of 339.39. Its purity consistently meets stringent industry standards, typically at 97%. Key physical properties include a melting point of 143-145 °C, a boiling point of 475.36 °C, and a flash point of 287.5±25.4 °C. With a density of 1.2270, this compound exhibits solubility in methanol, presenting only a very faint turbidity. For optimal stability and longevity, FMOC-L-Valine should be stored at temperatures ranging from 2-8°C. It is typically available in various package sizes, from grams for research to bulk quantities for industrial applications.


The primary application of FMOC-L-Valine lies within peptide synthesis, specifically utilizing the Fluorenylmethyloxycarbonyl (Fmoc) protecting group chemistry. Fmoc chemistry is a widely adopted method in solid-phase peptide synthesis (SPPS) due to its mild deprotection conditions, which avoid harsh acidic treatments that could damage sensitive peptide structures. L-Valine is an essential amino acid, and its Fmoc-protected form allows for precise, step-by-step assembly of peptides, which are fundamental building blocks for many modern therapeutics, including hormones, enzymes, and antibody fragments. The incorporation of FMOC-L-Valine ensures the integrity and stereochemical purity of the valine residue within the synthesized peptide chain, which is critical for the biological activity and safety of the final drug product.


Beyond its direct role in peptide synthesis, FMOC-L-Valine serves as a versatile chiral building block in the synthesis of a wide array of other pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its specific stereochemistry and reactive functional groups make it valuable for constructing complex organic molecules with desired biological activities. The global demand for high-quality pharmaceutical intermediates continues to rise, driven by innovation in biotechnology and the increasing complexity of new drug candidates. Manufacturers and researchers alike depend on reliable sources of such specialized compounds to support their development pipelines.


For those seeking to buy high-quality FMOC-L-Valine (CAS: 68858-20-8), NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer and supplier. We are committed to providing superior products that adhere to strict quality control measures, ensuring consistent purity and performance. Our extensive experience in chemical synthesis positions us as a reliable partner for your pharmaceutical research and production needs. We offer competitive price points for both small-scale research quantities and bulk orders. To inquire about purchase options or request detailed specifications, please contact us. Our dedicated team is ready to assist you in sourcing this essential pharmaceutical intermediate, ensuring a seamless and efficient supply chain for your critical projects.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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