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The pharmaceutical industry relies heavily on a vast array of specialized chemical intermediates to drive innovation in drug discovery and development. Among these, protected amino acids play a pivotal role, offering precise control over the synthesis of complex therapeutic molecules, particularly peptides and peptidomimetics. Fmoc-(S)-3-Amino-3-(4-bromophenyl)propionic acid, with its unique structural features, stands out as a critical compound in this domain.
Fmoc-(S)-3-Amino-3-(4-bromophenyl)propionic acid, identified by CAS number 220497-68-7, is an amino acid derivative that combines the robust Fmoc protecting group with a brominated phenyl ring attached to the beta-carbon. The Fmoc group is essential for enabling selective attachment and elongation in solid-phase peptide synthesis (SPPS), a cornerstone technique in creating peptides for therapeutic applications. Its base-labile nature allows for clean removal without damaging the peptide chain, ensuring high fidelity in synthesis.
The inclusion of a 4-bromophenyl moiety is particularly significant for pharmaceutical research. Bromine is an atom that can subtly alter a molecule's lipophilicity, metabolic stability, and binding interactions with biological targets. These modifications are often employed by medicinal chemists to optimize the pharmacokinetic profile (how the body processes a drug) and pharmacodynamic properties (how a drug affects the body) of potential drug candidates. Researchers looking to buy this compound for drug discovery projects benefit from its inherent versatility for further chemical modifications, such as palladium-catalyzed cross-coupling reactions.
When procuring such specialized intermediates, quality and consistency are paramount. Pharmaceutical research demands materials with high purity, typically exceeding 97%, to ensure reproducible results and avoid complications in complex synthetic routes. A reliable supplier, such as NINGBO INNO PHARMCHEM CO.,LTD., that acts as a dedicated manufacturer, can provide the necessary documentation, like Certificates of Analysis (CoA), to verify these critical specifications. Accessing these high-quality building blocks from a trusted source in China is often a strategic advantage for research institutions and pharmaceutical companies.
The application of Fmoc-(S)-3-Amino-3-(4-bromophenyl)propionic acid extends beyond conventional peptide synthesis. It is instrumental in the development of novel peptidomimetics, bioconjugates, and other complex organic molecules being investigated as therapeutic agents for a wide range of diseases. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the pharmaceutical industry by providing essential, high-purity chemical intermediates that drive cutting-edge research and development.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
