Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
The synergy between targeted molecular therapies and the body's immune system is rapidly transforming cancer treatment paradigms. Among the compounds at the forefront of this revolution is Galunisertib, known also as LY2157299 and identified by CAS 700874-72-2. This potent TGF-β receptor inhibitor is proving instrumental in not only directly impacting tumor growth but also in enhancing the effectiveness of cancer immunotherapies.
The TGF-β signaling pathway plays a dual role in cancer: it can suppress tumor growth in early stages but often promotes malignancy, metastasis, and immune evasion in established tumors. By inhibiting TGF-β receptor kinases, Galunisertib disrupts these pro-cancerous activities. A significant aspect of its therapeutic potential lies in its ability to counteract the immunosuppressive environment created by TGF-β within the tumor microenvironment. This involves reversing the suppression of T cell proliferation and enhancing the overall anti-tumor immune response.
For researchers and pharmaceutical developers, Galunisertib offers a unique opportunity to explore combination therapies. Its capacity to 'prime' the immune system makes it an attractive partner for agents like PD-1/PD-L1 checkpoint inhibitors, which aim to 'release the brakes' on immune cells. Pre-clinical studies have shown that combining Galunisertib with these immunotherapies can lead to improved tumor growth inhibition and even complete responses, a goal that has eluded many traditional treatments.
As a manufacturer and supplier of advanced pharmaceutical ingredients, we recognize the growing demand for high-quality Galunisertib. Our commitment is to provide researchers with a reliable source for this critical compound, enabling them to conduct vital studies and accelerate the development of next-generation cancer immunotherapies. Sourcing your LY2157299 from us ensures purity and consistency, which are paramount for valid scientific outcomes.
The potential of Galunisertib in driving innovation in cancer immunotherapy is immense. We invite research institutions and pharmaceutical companies to consider us as their trusted supplier for this advanced intermediate. Inquiry about purchasing Galunisertib and explore how our commitment to quality can support your pursuit of breakthrough cancer treatments.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
