NINGBO INNO PHARMCHEM CO.,LTD. is proud to present its high-quality Ribavirin Active Pharmaceutical Ingredient (API), a cornerstone in the global fight against various viral diseases. As a leading manufacturer and supplier of premium pharmaceutical raw materials, we are committed to providing products that meet the most stringent international standards, including GMP certification. Our Ribavirin stands as a testament to our dedication to excellence and public health.

Ribavirin, identified by its CAS No. 36791-04-5, is a synthetic guanosine analogue with the molecular formula C8H12N4O5 and a molecular weight of 244.20. It appears as a fine, white crystalline powder, odorless and with a characteristic taste. This versatile compound is renowned for its broad-spectrum antiviral properties, making it indispensable in modern medicine. Its remarkable efficacy against both RNA and DNA viruses positions it as a critical component in various therapeutic regimens.

The mechanism of action of Ribavirin is multifaceted. At a cellular level, its monophosphate metabolite acts as a competitive inhibitor of inosine monophosphate dehydrogenase (IMPDH), an enzyme crucial for the synthesis of guanosine triphosphate. This inhibition depletes intracellular GTP pools, thereby interfering with viral RNA synthesis. Furthermore, Ribavirin is known to induce lethal mutagenesis in viral genetic material, leading to an accumulation of errors that ultimately impair viral replication. Beyond these direct antiviral effects, Ribavirin also exhibits significant immunomodulatory properties, influencing pathways such as ERK, eIF4E, MNK1, EZH2, and MAPK, which can further bolster the host's response to infection.

The primary clinical applications of Ribavirin are well-established. It is widely used in the treatment of severe pneumonia in infants and young children caused by the Respiratory Syncytial Virus (RSV), typically administered via the inhalation route as a fine mist. Additionally, Ribavirin plays a vital role in the management of Hepatitis C virus (HCV) infection, where it is often prescribed in combination with interferon-alpha to enhance therapeutic outcomes and improve viral clearance rates. Ongoing research also explores its potential efficacy against other emerging viral threats, including Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), underscoring its relevance in future antiviral strategies.

At NINGBO INNO PHARMCHEM CO.,LTD., quality is paramount. Our Ribavirin API boasts an assay of 99.0% minimum purity, ensuring superior potency and consistency. We adhere to rigorous quality control measures, confirming that our product meets stringent specifications for loss on drying (≤ 5.0%), residue on ignition (≤ 0.5%), heavy metal content (≤ 20ppm), and arsenic content (≤ 5ppm). Each batch undergoes comprehensive testing to guarantee its pharmaceutical grade suitability and compliance with GMP guidelines. Our commitment to quality assurance means you can purchase with confidence.

For ease of transport and storage, our Ribavirin is typically packaged in 25kg drums, or custom packaging can be arranged upon request. To maintain its optimal quality and shelf life of two years, the product should be stored in a cool, dry, and well-closed container, protected from moisture and strong light or heat. We ensure prompt shipment with all necessary professional documentation, providing a seamless experience for our global clientele.

Whether you are looking to buy Ribavirin for research and development or require a reliable large-scale supplier for pharmaceutical production, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner. We offer competitive price options and flexible delivery terms to accommodate diverse client needs. For more information on our Ribavirin API or to inquire about a bulk purchase, please do not hesitate to contact our dedicated sales team. We are committed to fostering long-term partnerships by delivering exceptional products and unparalleled service as a leading Ribavirin manufacturer.