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Guanidine Hydrochloride (CAS 50-01-1), often abbreviated as GuHCl, is renowned for its potent chaotropic properties. These characteristics make it an indispensable tool in various scientific disciplines, from molecular biology to industrial applications. As a discerning researcher or a procurement specialist, understanding the full scope of its capabilities and knowing where to buy Guanidine Hydrochloride with confidence is key to successful project outcomes.
Understanding Chaotropic Agents: Guanidine Hydrochloride's Mechanism
Chaotropic agents are substances that disrupt the structure of water, thereby disrupting the hydrophobic effect that stabilizes protein structures. Guanidine Hydrochloride, typically used in concentrations ranging from 4M to 6M, excels in this role. It effectively unfolds proteins by breaking hydrogen bonds and hydrophobic interactions, denaturing them into their constituent polypeptide chains. This property is fundamental in molecular biology for tasks such as purifying DNA and RNA by separating them from cellular proteins. Researchers often seek a reliable Guanidine Hydrochloride supplier to ensure consistent denaturing capabilities for sensitive experiments.
Applications in Protein Purification and Nucleic Acid Extraction
In the realm of life sciences, Guanidine Hydrochloride is a staple. For protein purification, its ability to solubilize proteins and break down their tertiary and secondary structures is critical. It is particularly effective in clearing inclusion bodies formed during recombinant protein expression. Similarly, in nucleic acid extraction protocols, it serves as a powerful lysate that disrupts cellular components and inactivates nucleases like RNase, thereby preserving the integrity of the extracted DNA and RNA. The demand for high-purity Guanidine Hydrochloride for these applications means sourcing from a reputable Guanidine Hydrochloride CAS 50-01-1 manufacturer is essential.
Industrial Utility and Cost-Effectiveness
Beyond the laboratory, Guanidine Hydrochloride demonstrates significant industrial utility. It functions effectively as an antistatic agent, enhancing the properties of synthetic fibers in the textile industry. Its application in dye manufacturing also adds to its industrial importance. For companies in these sectors, investigating the Guanidine Hydrochloride price in China can lead to significant cost savings, especially for large-scale procurement. When considering wholesale Guanidine Hydrochloride for organic synthesis or industrial use, partnering with a manufacturer that guarantees quality and offers competitive pricing is a strategic advantage.
At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing high-quality Guanidine Hydrochloride that meets the rigorous demands of both scientific research and industrial applications. We are committed to being your dependable source for this versatile chemical. Reach out to us for a quote and to learn more about how our products can support your endeavors.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
