Heptyltriphenylphosphonium Bromide, identified by its Chemical Abstracts Service (CAS) number 13423-48-8, stands as a pivotal pharmaceutical intermediate and a highly versatile reagent in modern organic chemistry. This phosphonium salt, characterized by its unique chemical structure featuring a triphenylphosphonium cation and a heptyl group, is indispensable across numerous synthetic pathways. Its significant role in facilitating complex chemical transformations underscores its value in various scientific and industrial applications, particularly where precision and efficiency are paramount.
Typically appearing as a white to off-white fine crystalline powder, Heptyltriphenylphosphonium Bromide possesses a molecular formula of C25H30BrP and a molecular weight of approximately 441.39 g/mol. Its melting point ranges consistently between 173-176 °C. The compound is known to be hygroscopic, necessitating storage in an inert atmosphere and a cool, dry place to maintain its stability and high purity, which is critical for its performance in sensitive reactions. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the product maintains exceptional quality, typically offering a purity range that meets the most demanding specifications for pharmaceutical and research use.
At the heart of Heptyltriphenylphosphonium Bromide's utility is its function as an effective phase transfer catalyst. This remarkable property allows it to bridge the gap between immiscible phases, such as aqueous and organic solvents, enabling reactions that would otherwise be challenging or inefficient. By facilitating the transfer of reactants across these distinct environments, it significantly enhances reaction rates and yields. Furthermore, it is widely recognized as a key Wittig reagent, playing a crucial role in the Wittig reaction for the synthesis of olefins (alkenes) from aldehydes and ketones. This reaction is a cornerstone of organic synthesis, enabling the creation of carbon-carbon double bonds with high specificity.
The applications of Heptyltriphenylphosphonium Bromide are remarkably diverse and critical in various fields. In organic synthesis, it serves as an invaluable catalyst for a multitude of transformations, including nucleophilic substitutions, alkylations, and oxidations. Its ability to operate effectively in both polar and non-polar reaction media makes it a flexible tool for chemists designing intricate synthetic routes. Beyond general transformations, it contributes to stereospecific rearrangements, offering control over molecular architecture that is highly sought after in fine chemical and pharmaceutical production.
More specialized applications highlight its significance in advanced chemical synthesis. In polymer chemistry, Heptyltriphenylphosphonium Bromide is utilized in the controlled synthesis of polyelectrolytes and other functional polymers, aiding in the precise transfer of charged monomers and controlling polymer molecular weight and dispersity. It also plays a vital role in the synthesis of complex natural products and biologically active molecules. Examples include its use in the synthesis of male pheromones for insect control, the diastereoselective synthesis of climacostol, which exhibits promising antitumor activity, and the enantioselective synthesis of chiral vinylphosphonate and phosphonate analogs, including those related to the immunosuppressive agent FTY720. Its involvement in the preparation of embelin derivatives, known for their XIAP inhibitory and anticancer properties, further demonstrates its broad impact on medicinal chemistry research.
As a dedicated manufacturer and supplier of high-quality chemical compounds, NINGBO INNO PHARMCHEM CO.,LTD. understands the critical need for purity and consistency in pharmaceutical intermediates. We offer Heptyltriphenylphosphonium Bromide (CAS 13423-48-8) that meets stringent quality standards, ensuring its efficacy in your most demanding applications. For those looking to buy this essential phosphonium salt, competitive price options are available directly from our facility. We ensure a seamless purchase process and reliable delivery, solidifying our reputation as a trusted manufacturer and supplier in the global market. Our commitment to excellence makes NINGBO INNO PHARMCHEM CO.,LTD. the preferred choice for researchers and industrial clients seeking superior chemical intermediates.
In conclusion, Heptyltriphenylphosphonium Bromide (CAS 13423-48-8) remains an indispensable chemical entity due to its unique properties as a phase transfer catalyst and a versatile Wittig reagent. Its wide-ranging applications, from fundamental organic reactions to the synthesis of complex therapeutic agents, solidify its importance in the chemical and pharmaceutical industries. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a reliable partner, providing this high-grade compound with the assurance of quality and consistent supply to support innovation and progress worldwide.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.