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High Purity 2,4-Bis(trifluoromethyl)phenylboronic Acid: Essential for Advanced Synthesis

In the complex world of organic synthesis, access to high-quality building blocks is paramount. Among these, 2,4-Bis(trifluoromethyl)phenylboronic acid stands out as a crucial intermediate. This advanced chemical, typically supplied as a white crystalline powder, is engineered with specific properties that make it indispensable for creating sophisticated molecular structures required in various cutting-edge industries.

Chemically characterized by the presence of two powerful electron-withdrawing trifluoromethyl groups positioned on the phenyl ring, adjacent to the boronic acid functional group, this molecule exhibits unique reactivity. This structural feature significantly influences its performance in catalytic reactions. Ensuring a high level of purity, often verified by methods like HPLC (High-Performance Liquid Chromatography), is critical for achieving reproducible and efficient synthesis outcomes.

One of the primary applications where 2,4-Bis(trifluoromethyl)phenylboronic acid excels is in the Suzuki-Miyaura cross-coupling reaction. This palladium-catalyzed reaction is a cornerstone of modern organic synthesis, widely used for forming carbon-carbon bonds. The distinctive electronic nature of this boronic acid makes it particularly effective for coupling with a wide range of halides and pseudohalides, including challenging or sterically hindered substrates.

Beyond its utility in foundational coupling chemistry, this compound is a key precursor in the development of novel substances across several sectors. Its ability to efficiently introduce fluorinated moieties makes it invaluable in pharmaceutical synthesis, contributing to the creation of new drug candidates. Fluorinated compounds often exhibit enhanced metabolic stability, altered lipophilicity, and improved pharmacokinetic profiles, which are desirable attributes in medicinal chemistry. It is also vital in the synthesis of agrochemicals and specialized materials used in industries ranging from electronics to polymer science.

Manufacturing this high-performance intermediate demands stringent quality control measures. Adherence to rigorous production standards and comprehensive testing procedures for each batch ensures consistent product quality and reliability. Proper storage, typically under dry and inert conditions, is also essential to maintain its stability and reactivity over time.

Access to a reliable and consistent supply of 2,4-Bis(trifluoromethyl)phenylboronic acid is crucial for research and manufacturing operations. Experienced suppliers understand the importance of secure packaging and efficient logistics to ensure the product arrives in optimal condition, ready for immediate use in demanding synthetic procedures.

For businesses and researchers seeking to integrate this powerful building block into their processes, partnering with a trusted manufacturer and supplier is essential. Information regarding technical specifications, safety data, and bulk price options is readily available upon inquiry. Whether you need to buy a sample for evaluation or purchase larger quantities for production, finding a partner committed to quality and customer support is key to successful synthesis outcomes.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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