In the intricate landscape of pharmaceutical manufacturing, the availability of high-quality intermediates is paramount for the efficient and safe production of active pharmaceutical ingredients (APIs). One such vital compound is (2R)-2-amino-N-benzyl-3-methoxypropanamide, a crucial building block in the synthesis of Lacosamide, a widely recognized antiepileptic drug. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a reliable provider of this essential intermediate, adhering to the highest standards of purity and quality.

This compound, identified by CAS No. 196601-69-1, is also known by its synonym (R)-2-amino-N-benzyl-3-methoxypropanamide. Its molecular formula is C11H16N2O2, with a molecular weight of 208.25700. The physical and chemical properties of this intermediate are well-defined: it has a density of 1.107g/cm³, a boiling point of 421.947ºC at 760 mmHg, a flash point of 208.986ºC, a vapor pressure of 0mmHg at 25°C, and an index of refraction of 1.535. These precise specifications ensure its suitability for complex chemical reactions in pharmaceutical synthesis.

Our commitment to quality is reflected in the stringent specifications for (2R)-2-amino-N-benzyl-3-methoxypropanamide. It is typically supplied as a white to off-white powder, with an assay of ≥98.0% purity. This high level of purity is critical to ensure the integrity and efficacy of the final Lacosamide product. For packaging, it is available in 25 kg drums, with custom packaging options also available to meet specific customer requirements. Proper storage in a cool, ventilated place is recommended to maintain its stability and quality over time.

The primary application of (2R)-2-amino-N-benzyl-3-methoxypropanamide lies in its role as a key intermediate for Lacosamide (CAS: 175481-36-4). Lacosamide is a functionalized amino acid compound specifically developed as an anticonvulsive drug. It is prescribed for the adjunctive therapy of partial-onset seizures and, in some formulations, for primary generalized tonic-clonic seizures in patients with epilepsy. Its unique mechanism of action involves the selective enhancement of slow inactivation of voltage-gated sodium channels, which helps stabilize hyperexcitable neuronal membranes. Additionally, Lacosamide interacts with collapsin response mediator protein 2 (CRMP2), a phosphoprotein involved in neuronal development, though the exact role of this binding in seizure control is still being explored. The demand for Lacosamide underscores the importance of a reliable supply of its high-quality intermediates.

As a dedicated manufacturer and supplier of advanced pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. understands the critical role our products play in the global health sector. We ensure that our (2R)-2-amino-N-benzyl-3-methoxypropanamide meets the rigorous demands of pharmaceutical production, providing a consistent and high-performing raw material. For detailed price information, or to inquire about how to buy or purchase this essential Lacosamide intermediate, please do not hesitate to contact us. We are committed to fostering partnerships and supporting pharmaceutical companies worldwide with superior chemical products and reliable service.