In the dynamic landscape of chemical synthesis and materials science, the availability of high-quality building blocks is paramount. Among these crucial compounds, 4-Fluoro-3-Iodo-1h-Indazole, identified by its CAS number 518990-32-4, stands out as a versatile and highly sought-after intermediate. This compound, a white powder with the molecular formula C7H4FIN2, possesses a unique structural profile that makes it invaluable in the synthesis of a wide array of complex molecules.

The core structure of 4-Fluoro-3-Iodo-1h-Indazole is the indazole ring, a bicyclic aromatic system containing a benzene ring fused to a pyrazole ring. This scaffold is a privileged structure in medicinal chemistry, frequently found in biologically active compounds. The presence of a fluorine atom at the 4-position and an iodine atom at the 3-position introduces specific electronic and steric properties. These functional groups serve as strategic handles for further chemical transformations, including various coupling reactions, nucleophilic substitutions, and cyclizations, enabling chemists to construct intricate molecular architectures with high precision.

The pharmaceutical industry is a major consumer of intermediates like 4-Fluoro-3-Iodo-1h-Indazole. Its indazole core, decorated with halogen substituents, is a common motif in drug discovery. It serves as a fundamental building block for the synthesis of numerous active pharmaceutical ingredients (APIs), particularly kinase inhibitors, which are crucial in cancer therapy, and other therapeutic agents targeting a range of diseases. The compound's high purity, typically exceeding 99%, is essential for these demanding applications, where even trace impurities can affect the final product's efficacy, safety, and regulatory compliance. Manufacturers adhering to stringent quality control standards are vital for supplying this critical intermediate to pharmaceutical research and manufacturing.

Beyond pharmaceuticals, the utility of 4-Fluoro-3-Iodo-1h-Indazole extends to other specialized fields. Its potential applications have been explored in various chemical processes and material developments. While specific uses vary, the reactivity endowed by the iodine and fluorine atoms on the indazole core makes it suitable for incorporation into polymers, dyes, agrochemicals, and specialized electronic materials. The versatility stems from its ability to participate in palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Heck couplings, which are cornerstones of modern organic synthesis, allowing for the facile introduction of diverse substituents.

Quality assurance is a non-negotiable aspect when dealing with chemical raw materials of this importance. A high purity level, often specified as 99% or higher, ensures predictable reactivity and minimizes the need for extensive purification downstream. Reputable suppliers implement rigorous testing protocols, including techniques like High-Performance Liquid Chromatography (HPLC), Gas Chromatography-Mass Spectrometry (GC-MS), and Nuclear Magnetic Resonance (NMR), to confirm identity, purity, and absence of impurities. Batch-to-batch consistency is another critical factor, ensuring reproducible results in synthesis and manufacturing processes. This commitment to quality is reflected in certifications and robust internal quality management systems.

The physical form of 4-Fluoro-3-Iodo-1h-Indazole as a white powder facilitates handling, storage, and transportation. Proper packaging is essential to maintain its integrity, protect it from moisture and light, and ensure safe transit. Packaging options typically range from small bags or bottles for laboratory use to larger drums or bags for bulk industrial applications, depending on the quantity required. Secure and compliant packaging is a standard practice among reliable chemical suppliers.

Logistics and supply chain efficiency are crucial in the chemical industry. The timely delivery of intermediates like 4-Fluoro-3-Iodo-1h-Indazole is critical for manufacturers relying on a steady supply for their production schedules. Experienced suppliers offer various shipping methods, including express courier services for smaller quantities and air or sea freight for larger volumes, to cater to different customer needs and geographical locations. Efficient warehousing and inventory management also play a significant role in ensuring product availability and reducing lead times.

The global market for fine chemicals and pharmaceutical intermediates is constantly evolving, driven by innovation in drug discovery and advancements in material science. The demand for high-purity building blocks like 4-Fluoro-3-Iodo-1h-Indazole is expected to remain strong due to its established and emerging applications. Identifying a trusted and capable manufacturer or supplier is key for businesses requiring this material. Factors to consider include the supplier's production capacity, quality control capabilities, reliability in delivery, and competitive price.

Prospective customers looking to buy or purchase 4-Fluoro-3-Iodo-1h-Indazole (CAS 518990-32-4) should engage directly with reputable sources. Inquiring about minimum order quantities (MOQ), lead times, packaging options, and payment terms is advisable. Many suppliers offer samples for evaluation before committing to a bulk purchase. Establishing a long-term relationship with a consistent and quality-focused supplier ensures a stable source for this important chemical intermediate.

For information regarding the price and availability of high-purity 4-Fluoro-3-Iodo-1h-Indazole, potential buyers are encouraged to contact NINGBO INNO PHARMCHEM CO.,LTD. We are a dedicated manufacturer and supplier committed to providing quality chemical raw materials. Whether you need to buy a sample quantity or are planning a large-scale purchase, our team is ready to assist with detailed product specifications and competitive pricing. Partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is essential for the success of your chemical synthesis projects.