We are pleased to present information on 6-Chloronicotinic acid, a crucial chemical intermediate recognized by its CAS number 5326-23-8. Also known by synonyms such as 6-chloropyridine-3-carboxylic acid, this compound plays a vital role in various chemical synthesis processes, particularly within the pharmaceutical industry. Its unique chemical structure, represented by the molecular formula C6H4ClNO2 and a molecular weight of 157.55400, makes it an indispensable building block for complex organic molecules.

Understanding the physical and chemical properties of 6-Chloronicotinic acid is essential for its safe handling and effective use. This substance typically presents as a white or light yellow powder. Key properties include a density of approximately 0.5 g/cm³ and a melting point around 190°C (with decomposition). Its boiling point is estimated at 330.1°C at 760 mmHg, and it has a flash point of 192°C. These characteristics underscore the need for appropriate storage and handling procedures, emphasizing storage in a cool, dry, well-closed container, away from moisture and strong light or heat sources.

Quality assurance is paramount for chemical intermediates used in sensitive applications like pharmaceuticals. Our 6-Chloronicotinic acid adheres to stringent quality specifications. The standard requires a purity of at least 99%. Other important parameters include a maximum water content of 0.5% and a residue on ignition limit of 0.5%. Recent test results consistently demonstrate the high quality of our material, showing moisture content around 0.11%, individual impurities at 0.14%, and a high purity level of 99.58%, comfortably meeting or exceeding factory standards.

The primary application of 6-Chloronicotinic acid is as a key intermediate in the synthesis of Tazarotene. Tazarotene (CAS: 118292-40-3) is a retinoid medication widely used in dermatology. The reliable supply of high-purity 6-Chloronicotinic acid is therefore critical for manufacturers producing Tazarotene for therapeutic applications. Its specific reactivity and structural features make it an ideal precursor in the multi-step synthesis required for this important active pharmaceutical ingredient (API).

6-Chloronicotinic acid is typically supplied in 25kg cardboard drums, though packaging can be customized according to specific customer requirements. As a reliable manufacturer and supplier of this intermediate, we ensure consistent quality and availability.

For those seeking to buy or purchase high-purity 6-Chloronicotinic acid (CAS 5326-23-8), understanding factors like lead time, minimum order quantity, and current price is important. We encourage inquiries regarding detailed specifications, sample availability, and pricing for bulk orders. Finding a trustworthy supplier is crucial for maintaining the integrity and efficiency of your synthesis processes. We are committed to providing quality chemical intermediates to support your production needs.