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NINGBO INNO PHARMCHEM CO.,LTD. proudly presents 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one, a crucial chemical intermediate with CAS No. 20925-64-8. This compound, also known by synonyms such as 7,8-dimethoxy-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepine and 1,3,4,5-Tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one, plays an indispensable role in the pharmaceutical industry, particularly in the synthesis of vital active pharmaceutical ingredients (APIs).
Our 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one is characterized by its white to off-white crystalline powder appearance and boasts an assay of ≥98.0% purity, ensuring the highest quality for your applications. Its molecular formula is C12H15NO3, with a molecular weight of 221.252 g/mol. Key physical and chemical properties include a predicted density of approximately 1.1 g/cm3, a boiling point of around 438.2±45.0 °C at 760 mmHg, and a flash point of 218.8±28.7 °C. The vapor pressure is minimal, approximately 0.0±1.1 mmHg at 25°C, and its index of refraction is around 1.528. These specifications underscore its stability and suitability for rigorous chemical processes.
The primary application of this intermediate is in the complex multi-step synthesis of Ivabradine (CAS: 155974-00-8) and its hydrochloride salt, Ivabradine hydrochloride (CAS: 148849-67-6). Ivabradine is a highly significant medication used in cardiology to treat chronic stable angina and chronic heart failure. Its mechanism involves selectively and specifically inhibiting the I(f) current in the cardiac sinoatrial node, thereby reducing heart rate without affecting myocardial contractility or repolarization. As a key precursor, the quality of 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one directly impacts the efficacy and safety of the final Ivabradine API, making its high purity and consistent quality paramount for pharmaceutical manufacturers.
At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing top-tier chemical compounds. Our production processes adhere to stringent quality control standards, from raw material sourcing to final product packaging. We ensure that every batch of 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one meets the specified purity and physical properties, providing our clients with a reliable and consistent supply. For optimal preservation of product integrity, it is recommended to store this compound in a cool, ventilated place, shielded from direct sunlight and moisture.
As a leading manufacturer and supplier of high-quality pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. offers flexible packaging options, including our standard 25 kg/drum, with the capability to customize packaging according to specific customer requirements. Our robust supply chain ensures efficient delivery to clients worldwide. For detailed product specifications, current price information, or to inquire about large-scale purchase orders, please contact our sales team. We are dedicated to supporting your research and manufacturing needs with superior chemical solutions. Please note, this product is intended for research use only and not for diagnostic or therapeutic use.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
