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Aztreonam: A Critical Monobactam Antibiotic API from NINGBO INNO PHARMCHEM CO.,LTD.
In the realm of modern pharmaceuticals, the availability of high-quality Active Pharmaceutical Ingredients (APIs) is fundamental to developing effective and safe treatments. Among these vital components, Aztreonam stands out as a crucial monobactam antibiotic, playing a significant role in combating serious bacterial infections. NINGBO INNO PHARMCHEM CO.,LTD. is pleased to highlight its offering of high-purity Aztreonam powder, identified by its CAS Number 78110-38-0, a key raw material for pharmaceutical formulations.
Aztreonam is a synthetic antibiotic belonging to the monobactam class. Its distinct structure, featuring a monocyclic beta-lactam ring, provides a unique mechanism of action and a favorable safety profile compared to other beta-lactams, particularly regarding hypersensitivity reactions. This makes it an invaluable option for treating patients who have experienced allergic reactions to penicillin or cephalosporin antibiotics.
The primary utility of Aztreonam lies in its potent activity against a wide spectrum of aerobic Gram-negative bacteria. Unlike many other beta-lactams, it shows limited activity against Gram-positive bacteria and anaerobic organisms. This targeted spectrum is highly beneficial in treating infections specifically caused by problematic Gram-negative pathogens, such as Pseudomonas aeruginosa, Enterobacter species, Klebsiella pneumoniae, and others. These bacteria are often responsible for difficult-to-treat hospital-acquired infections.
Clinical applications for Aztreonam API derived pharmaceuticals are extensive. It is commonly employed in the treatment of:
The mechanism by which Aztreonam exerts its antibacterial effect involves the inhibition of bacterial cell wall synthesis. It specifically binds to penicillin-binding proteins (PBPs) located in the bacterial membrane, particularly PBP-3 in Gram-negative bacteria. This binding disrupts the cross-linking of peptidoglycans, essential components of the bacterial cell wall, leading to cell lysis and death. Its high affinity for PBP-3 in Gram-negative bacteria explains its targeted spectrum.
Quality is paramount when sourcing pharmaceutical raw materials. NINGBO INNO PHARMCHEM CO.,LTD. understands this critical requirement and ensures that its Aztreonam powder meets stringent quality specifications. The product is supplied as a white or yellowish crystalline powder with a high purity level, typically exceeding 99%. Key parameters such as specific rotation, pH, water content, related substances (including Desulfonated Aztreonam and Aztreonam E-isomer), residual solvents, heavy metals, bacterial endotoxins, and sterility are carefully controlled and tested to ensure consistency and suitability for pharmaceutical use. The material aligns with recognized pharmacopoeial standards, providing confidence in its quality and performance.
Sourcing Aztreonam powder from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. offers numerous advantages. With a focus on quality control and adherence to international standards such as ISO 9001, the company is dedicated to providing reliable and consistent products. The manufacturing processes are designed to produce Aztreonam API that meets the demanding requirements of pharmaceutical production globally.
The supply chain management at NINGBO INNO PHARMCHEM CO.,LTD. is optimized to ensure timely delivery and secure packaging. Aztreonam powder is typically packaged in foil-alum bags or paper drums, with common sizes including 25kg drums or bags, tailored to meet the logistical needs of pharmaceutical manufacturers worldwide. Custom packaging options may also be available upon request.
As a dedicated supplier of pharmaceutical raw materials and fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is committed to fostering long-term partnerships with pharmaceutical companies and research institutions. The availability of high-purity Aztreonam powder is a testament to this commitment, providing access to a critical API for the development and manufacturing of life-saving antibiotic medications.
For companies seeking a dependable Aztreonam manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. represents a trusted source. Inquiries regarding the technical specifications, availability, and Aztreonam price are welcome. Understanding how to buy Aztreonam in various quantities for development or commercial production is made straightforward through their professional sales and technical support teams. Pharmaceutical companies looking to purchase Aztreonam API powder of consistent and verifiable quality are encouraged to contact NINGBO INNO PHARMCHEM CO.,LTD. to discuss their specific needs and procurement strategies.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
