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High-Purity Benzyl Chloride (CAS 100-44-7) for Industrial Synthesis

Benzyl Chloride (C6H5CH2Cl, CAS 100-44-7) is a foundational organic compound serving as a vital intermediate across numerous chemical industries. As a colorless to pale yellow liquid, it is characterized by a distinct aromatic odor. Its significance stems from its high reactivity, primarily attributed to the presence of the reactive chloromethyl group attached to a stable benzene ring. This structural feature makes benzyl chloride an exceptionally versatile building block for introducing the benzyl moiety into a wide array of molecules.

With a molecular weight of approximately 126.59 g/mol, benzyl chloride undergoes facile nucleophilic substitution reactions. This inherent reactivity is key to its extensive use in synthesizing more complex organic structures. Its applications span diverse sectors, reflecting its indispensable role in modern chemical manufacturing processes.

One of the primary uses of benzyl chloride is in organic synthesis. It acts as a crucial precursor for creating various important compounds. For example, reactions with ammonia or primary amines yield benzylamines, while reactions with alcohols or phenols produce benzylethers. Similarly, interacting with carboxylic acids or their derivatives leads to the formation of benzyl esters. These derivatives themselves are valuable intermediates or end products in different industries.

The pharmaceutical industry heavily relies on benzyl chloride for the synthesis of numerous intermediates and active pharmaceutical ingredients (APIs). Its ability to easily introduce a benzyl group allows for the creation of complex molecular structures necessary for therapeutic agents. Specific applications include its role in the synthesis of certain antidepressant drugs and local anesthetic agents, highlighting its importance in medicinal chemistry.

In the fragrance and flavor industry, benzyl chloride is instrumental in the production of aromatic compounds. A notable example is its use in synthesizing benzyl acetate, a common fragrance component found in floral scents like jasmine. Its derivatives contribute significantly to the palette of scents and flavors available to perfumers and food scientists.

The compound is also employed in the production of dyes and pigments. Specifically, it is involved in the synthesis of certain azo dyes, which are widely utilized in textile dyeing and printing processes, contributing to the vibrant colors seen in fabrics globally.

Furthermore, benzyl chloride finds application in the manufacture of surface active agents and additives, such as quaternary ammonium compounds. These compounds are integral components of detergents, fabric softeners, and other cleaning and personal care products, contributing to their functional properties.

Typical specifications for high-purity benzyl chloride emphasize its quality parameters. A common purity standard is 99.5% minimum. Appearance is usually specified as a transparent liquid, with a density in the range of 1.099-1.105 g/cm³ and minimal moisture content, typically 0.03% maximum. Color is measured using the Hazen scale, often specified as 20 max. Other physical properties like boiling point (around 197°C), flash point (around 67°C), refractive index (around 1.5415), and freezing point (around -43°C) are also important indicators of its quality and handling characteristics.

The inherent properties of benzyl chloride, including its reactivity and physical characteristics, necessitate careful handling and storage. While widely used, understanding its chemical nature and adhering to safety guidelines are paramount in industrial settings.

In summary, Benzyl Chloride (CAS 100-44-7) stands as a critical chemical intermediate due to its versatile reactivity and broad application spectrum. Its role in organic synthesis, pharmaceuticals, flavors, fragrances, dyes, and surfactants underscores its value in the chemical manufacturing landscape. Ensuring high purity, often specified at 99.5% minimum, is crucial for its effective use in sensitive applications like pharmaceutical synthesis and high-quality fragrance production.

For businesses seeking a reliable manufacturer or supplier of high-purity Benzyl Chloride, exploring established channels is essential. The price of Benzyl Chloride can vary based on factors such as purity, quantity, packaging, and global market conditions. To buy or purchase this crucial intermediate, potential buyers typically engage with experienced chemical distributors or manufacturers directly, inquiring about current price, minimum order quantity, and quality certifications. Securing a consistent and quality-assured supply is vital for downstream industries relying on this versatile compound for their production needs.

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