Ceftazidime Dihydrochloride, identified by the CAS number 73547-70-3, stands as a critical and essential pharmaceutical intermediate. Its primary role is as a key building block in the complex synthesis process of Ceftazidime, a widely used third-generation cephalosporin antibiotic. The purity and quality of this intermediate directly impact the efficacy, safety, and overall quality of the final active pharmaceutical ingredient (API), Ceftazidime.

This compound typically presents as a high purity white powder. Its chemical identity is precisely defined by the molecular formula C₂₂H₂₃N₆O₇S₂ . Cl . HCl and a molecular weight of 619.49. The high purity level, often exceeding 98%, is paramount for its intended pharmaceutical application. Impurities in pharmaceutical intermediates can lead to side reactions during synthesis, reduce yield, or introduce undesirable substances into the final drug product, posing health risks.

Ceftazidime, the final API derived from this intermediate, is renowned for its broad spectrum of activity against a wide range of Gram-negative and some Gram-positive bacteria. It is commonly prescribed for the treatment of severe infections, including pneumonia, meningitis, sepsis, and complicated urinary tract infections. Its mechanism of action involves inhibiting bacterial cell wall synthesis, a crucial process for bacterial survival. The demand for Ceftazidime API is significant globally, which in turn drives the demand for high-quality Ceftazidime Dihydrochloride intermediate.

The production of pharmaceutical intermediates like Ceftazidime Dihydrochloride requires stringent adherence to quality control measures and regulatory standards. Leading suppliers operate under internationally recognized quality management systems such as ISO 9001 and follow the principles of Good Manufacturing Practices (GMP). These certifications assure customers of consistent product quality, process reliability, and traceability. Each batch of the product undergoes rigorous testing to verify its purity, composition, and physical properties, documented through a comprehensive Certificate of Analysis (CoA).

For pharmaceutical manufacturers, sourcing reliable and high-quality intermediates is a strategic decision. A dependable supplier not only provides a product meeting specifications but also offers stability in the supply chain, technical support, and expertise. The manufacturing process for Ceftazidime Dihydrochloride involves intricate chemical reactions, demanding precise control over parameters such as temperature, pressure, reaction time, and reagent purity. Skilled personnel and advanced analytical equipment are indispensable to ensure the consistent production of material that meets the required pharmaceutical grade.

Scalability of production is another vital aspect. As the global demand for Ceftazidime fluctuates, the supplier must have the capacity to scale production efficiently without compromising on quality. This requires robust manufacturing infrastructure, optimized processes, and effective inventory management. Furthermore, secure and timely logistics are essential to ensure the product reaches the customer's manufacturing facility in optimal condition, ready for use in the synthesis of the final API.

Investing in research and development is also a hallmark of a leading intermediate supplier. Continuous process optimization can lead to improved yields, reduced environmental impact, and enhanced product consistency. Technical teams are often available to provide support, address customer queries, and collaborate on specific requirements, fostering strong partnerships built on trust and mutual benefit.

Navigating the procurement process for pharmaceutical intermediates can be complex. When seeking a reliable supplier for High Purity Ceftazidime Dihydrochloride CAS 73547-70-3, prospective buyers should consider factors such as manufacturing capabilities, quality certifications, regulatory compliance history, and supply chain stability. Discussing the price structure, minimum order quantities, and lead times is a crucial part of the initial engagement. Detailed technical specifications and sample evaluation are also standard procedures before committing to bulk purchase. Understanding the complete process, from manufacturing through quality control to logistics, helps ensure a smooth and efficient procurement experience. Connecting directly with the manufacturer or their authorized representatives is often the most effective way to initiate the process to buy this essential intermediate, ensuring transparency and direct communication regarding product details, quality assurance, and logistical arrangements necessary for global distribution.