Deoxycholic Acid, identified by CAS Registry Number 83-44-3, stands as a crucial secondary bile acid produced in the liver. This vital compound plays a significant role in the human digestive system, primarily facilitating the emulsification and absorption of fats and fat-soluble vitamins in the intestine. As a high-purity chemical intermediate, typically presented in a fine powder form with a minimum purity specification often exceeding 99%, Deoxycholic Acid (CAS 83-44-3) is a key raw material with diverse applications.

The physical and chemical properties of Deoxycholic Acid (CAS 83-44-3) are well-defined. It possesses a molecular formula of C₂₄H₄₀O₄ and a molecular weight of 392.58 g/mol. Its melting point typically ranges between 172-178 ºC, indicating a solid crystalline structure at room temperature. The compound exhibits limited water solubility, approximately 0.24 g/L at 15 ºC, highlighting its hydrophobic nature consistent with its function in lipid metabolism. Its specific rotation (alpha) is recorded at 55 º (c=1, EtOH), a key parameter for quality verification and identification.

Beyond its fundamental digestive role, Deoxycholic Acid (CAS 83-44-3) offers a range of physiological benefits that translate into its utility in pharmaceutical and health-related applications. One primary function is its ability to promote bile secretion. By increasing bile flow and improving gallbladder contraction function, it aids the body in eliminating waste products and cholesterol, contributing to overall detoxification processes. This action is particularly beneficial in managing conditions related to sluggish bile flow or impaired gallbladder function.

Furthermore, Deoxycholic Acid is a potent aid in fat digestion. It acts as a natural detergent, breaking down large fat globules into smaller micelles. This emulsification process significantly increases the surface area available for pancreatic lipase enzymes to act upon, thereby accelerating the breakdown of dietary fats into absorbable fatty acids and glycerol. This function is essential for efficient nutrient absorption and can be leveraged in formulations aimed at improving digestive health.

Research also suggests potential bacteriolytic properties of Deoxycholic Acid. It may contribute to disrupting the cell walls of certain bacteria, offering a protective effect within the gastrointestinal tract. This lytic activity, combined with its role in maintaining healthy bile flow, supports a balanced gut environment and can influence the composition of the gut microbiota.

The compound is also known for its ability to reduce bile viscosity. By influencing the composition of bile, particularly reducing the concentration of cholesterol, Deoxycholic Acid helps prevent the formation of cholesterol gallstones and facilitates the smoother flow of bile through the biliary ducts. This property is central to its use in managing or preventing cholelithiasis and other related conditions.

Moreover, Deoxycholic Acid demonstrates anti-inflammatory effects. Studies indicate its potential to inhibit the activation of macrophages and reduce the release of inflammatory mediators. This immunomodulatory action suggests therapeutic potential in mitigating inflammation associated with various conditions, including certain liver and gastrointestinal disorders.

The therapeutic applications of Deoxycholic Acid (CAS 83-44-3) extend to the treatment of specific medical conditions where its functions are beneficial. It is utilized as a drug that promotes bile secretion, helping to clear bile blockages. It is employed for patients experiencing gallbladder and biliary tract dysfunction, aiding in restoring normal bile flow and digestion. It can also be used in the context of post-cholecystectomy syndrome to support digestive function after gallbladder removal. Additionally, its properties make it a consideration in the management of chronic cholecystitis, cholelithiasis (contributing to stone dissolution or prevention), and potentially as an adjunct in the treatment of chronic hepatitis by improving liver function and bile metabolism.

Sourcing high-quality Deoxycholic Acid (CAS 83-44-3) is paramount for its effective use in pharmaceutical, research, or other applications. Reliable production methods, often involving hydrolysis, ensure the desired purity level, typically 99% min. The availability of this raw material is supported by established production capacities, ensuring a consistent supply for global demand. Proper handling and packaging, such as 25kg drums, maintain product integrity during transport and storage, which is typically stable for at least 2 years under suitable conditions.

For businesses and researchers globally, finding a trustworthy manufacturer and supplier of Deoxycholic Acid (CAS 83-44-3) is essential for securing their supply chain. NINGBO INNO PHARMCHEM CO.,LTD. is a provider of this high-purity chemical. Understanding the typical order process, including minimum order quantities and estimated delivery times for various shipping methods (such as express, air, or sea transport), is crucial for planning procurement. Inquiries regarding the current price of Deoxycholic Acid (CAS 83-44-3) and terms for bulk orders are welcomed. Businesses looking to buy or purchase this versatile ingredient can reach out to discuss their specific requirements and obtain detailed quotations.