Dimethyl Formamide (DMF) is a key organic compound with the formula (CH₃)₂NC(O)H.
It is a colorless liquid widely recognized for its miscibility with water and the vast majority of organic liquids.
DMF is commonly abbreviated as DMF and is a highly effective and common solvent used in numerous chemical reactions and industrial processes.
Classified as a polar (hydrophilic) aprotic solvent, DMF possesses a high boiling point, making it suitable for reactions carried out at elevated temperatures.
Its polar nature facilitates reactions that follow polar mechanisms, such as SN2 reactions.
While pure Dimethyl Formamide is essentially odorless, technical-grade or samples that have undergone degradation may emit a fishy smell.
This characteristic odor is typically due to the presence of dimethylamine, an impurity resulting from degradation.
Chemically, DMF is a derivative of formamide, which is the amide of formic acid.
It is reactive under certain conditions; for instance, DMF can be hydrolyzed by strong acids and bases, particularly when heated, yielding formate and dimethylamine upon reaction with sodium hydroxide.
Near its boiling point, DMF can also undergo decarbonylation, producing dimethylamine and carbon monoxide.
Consequently, distillation procedures involving DMF are usually conducted under reduced pressure to allow for lower operating temperatures.
In the realm of organic synthesis, DMF serves as a significant reagent in several important transformations.
A notable example is the Vilsmeier-Haack reaction, where DMF is used to formylate aromatic compounds.
This process involves the initial conversion of DMF into a reactive chloroiminium ion, which then attacks the aromatic ring.
Furthermore, organolithium compounds and Grignard reagents react with DMF, producing aldehydes upon subsequent hydrolysis in a reaction known as the Bouveault reaction.
The primary and most widespread application of Dimethyl Formamide is its use as a solvent.
Its low evaporation rate, combined with its excellent dissolving capabilities for a wide range of substances, makes it invaluable.
DMF is extensively used in the production of acrylic fibers, often employed in the wet spinning process.
It also serves as a solvent in the manufacture of various plastics, including polyurethanes, synthetic leathers, films, and surface coatings, contributing to the quality and processing efficiency of these materials.
Beyond polymers and materials, DMF finds crucial roles in the chemical and pharmaceutical industries.
It is utilized as a solvent in peptide coupling processes for the synthesis of pharmaceuticals.
Moreover, DMF is employed in the development and production of pesticides, acting as a solvent or reaction medium.
In research laboratories, DMF is a staple reagent due to its versatility and common availability.
It is effective at separating and suspending carbon nanotubes, a property useful in nanotechnology research.
DMF can function as a standard in proton NMR spectroscopy for quantitative analysis.
In the synthesis of organometallic compounds, it can serve as a source of carbon monoxide ligands.
DMF is also a common solvent utilized in electrospinning techniques for generating nanofibers.
Furthermore, it plays a key role in the solvothermal synthesis of Metal-Organic Frameworks (MOFs), a class of porous materials with diverse applications.
Deuterated DMF (DMF-d7) is even used as a reagent for the deuteration of polyaromatic hydrocarbons under specific conditions.
Ensuring the quality of Dimethyl Formamide is paramount for its various applications.
High-purity DMF is typically specified by parameters including color (Pt-Co chrominance), minimal levels of impurities like dimethylamine and formic acid, pH, electric conductivity, moisture content, and trace metals like iron.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying DMF that meets rigorous industry standards, ensuring a minimum purity of 99.95%.
NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of reliable packaging and logistics.
High-purity Dimethyl Formamide is available in various standard packaging options to suit different needs, including robust iron drums (typically 190kg) and ISO tanks (approximately 22 tons), facilitating efficient bulk transport.
We work with professional shipping lines to ensure prompt and reliable delivery, with typical shipping times ranging from 7 to 14 days after receipt of deposit or original LC.
As a dedicated supplier, NINGBO INNO PHARMCHEM CO.,LTD. focuses on providing high-quality chemical raw materials like Dimethyl Formamide.
Our commitment to a comprehensive quality assurance system ensures the stability and qualification of the product supplied.
We aim to build mutual trust and long-term partnerships with customers globally by adhering to principles of honesty and integrity.
Our team is ready to provide quick and clear responses to inquiries and offer professional support.
When seeking a reliable manufacturer and supplier of high-purity Dimethyl Formamide, considering NINGBO INNO PHARMCHEM CO.,LTD. is essential.
Understanding the market price and ensuring a smooth purchase process are key factors we address.
We offer competitive options for customers looking to buy DMF in various quantities, from drums to ISO tanks.
For inquiries regarding price, availability, or technical specifications, please contact NINGBO INNO PHARMCHEM CO.,LTD.
We are ready to facilitate your purchase and discuss your specific requirements for Dimethyl Formamide supply.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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