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NINGBO INNO PHARMCHEM CO.,LTD. is pleased to announce the availability of high-quality Doxazosin Mesylate, a key Active Pharmaceutical Ingredient (API) widely used in the pharmaceutical industry. Identified by its CAS number 74191-85-8, Doxazosin Mesylate is a critical raw material for manufacturing medications targeting significant health conditions, primarily benign prostatic hyperplasia (BPH) and hypertension.
Doxazosin Mesylate is a quinazoline derivative that functions as a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. This mechanism makes it effective in relaxing smooth muscle in blood vessels, thus lowering blood pressure, and in the prostate and bladder neck, which alleviates symptoms associated with BPH. Its chemical designation is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) methanesulfonate. The empirical formula is C23H25N5O5 • CH4O3S, and it has a molecular weight of 547.6.
This compound presents as a white powder. Its solubility profile is important for pharmaceutical formulation; it is freely soluble in dimethylsulfoxide, soluble in dimethylformamide, slightly soluble in methanol, ethanol, and water (specifically 0.8% at 25°C), and very slightly soluble in methylene chloride. These properties are essential for formulators developing various dosage forms, predominantly oral tablets.
At NINGBO INNO PHARMCHEM CO.,LTD., we understand the critical importance of purity and consistency for pharmaceutical raw materials. Our Doxazosin Mesylate is manufactured under strict quality control protocols to ensure it meets or exceeds international pharmacopoeia standards, such as the USP standard. Rigorous testing is conducted to confirm its specifications:
The primary therapeutic applications of Doxazosin Mesylate are well-established. In the treatment of benign prostatic hyperplasia (BPH), it helps to relax the muscles in the prostate and bladder neck, improving urine flow and reducing symptoms like difficulty starting urination, weak stream, and frequent urination. For hypertension, it works by blocking alpha-1 receptors in the walls of blood vessels, causing them to relax and widen, which lowers blood pressure. The reliability and quality of the API are paramount for the efficacy and safety of the final medicinal product used by patients worldwide.
Proper handling and storage are vital to maintain the quality and stability of Doxazosin Mesylate. It should be stored in a cool, dry place, away from strong light and heat. When stored correctly under these conditions, it has a shelf life of 2 years, ensuring its viability for manufacturing processes over a reasonable period. Standard packaging for transport and storage is typically 25kg per drum, designed to protect the product's integrity during transit and storage.
NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a reliable partner for pharmaceutical companies globally. As an experienced manufacturer and supplier of pharmaceutical raw materials, we ensure robust supply chain management, technical support, and consistently high product quality. We understand the complexities of the pharmaceutical industry and the necessity for dependable sourcing.
For companies looking to buy or purchase high-quality Doxazosin Mesylate API (CAS 74191-85-8), NINGBO INNO PHARMCHEM CO.,LTD. offers competitive options. Detailed price information is available upon inquiry, with tiered pricing based on quantity, reflecting potential savings for bulk orders. While standard MOQ is flexible, cost efficiencies are typically realized at higher volumes. For example, preliminary indications suggest pricing structures that become more favorable at quantities of 50 kg and significantly more so at 500 kg and above, though specific quotes should be requested based on current market conditions and requirements.
We encourage potential partners and customers to reach out to discuss their specific needs for Doxazosin Mesylate. Whether you are a large-scale pharmaceutical manufacturer or a smaller entity requiring a trusted supplier, NINGBO INNO PHARMCHEM CO.,LTD. is equipped to meet your demands for this essential API. Contact us today to learn more about our product, request technical documentation, or obtain a detailed quotation. Partner with a company committed to quality, reliability, and customer satisfaction in the pharmaceutical raw material market.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
