NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight its premier product, 99% Pure Estradiol 17-Enanthate Powder, identified by its CAS number 4956-37-0. This high-purity compound is a cornerstone in various pharmaceutical applications, renowned for its efficacy and stability. As a leading manufacturer in the pharmaceutical intermediates industry, we are committed to providing our global clientele with products that meet the most stringent quality standards. This article delves into the chemical properties, primary applications, and the critical importance of purity for Estradiol 17-Enanthate.

What is Estradiol 17-Enanthate?
Estradiol 17-Enanthate, with the chemical formula C₂₅H₃₆O₃, is a synthetic ester, specifically the 17-heptanoyl ester, of the natural estrogen, 17β-estradiol. It functions as a prodrug of estradiol, meaning it is converted into the active hormone within the body after administration. This conversion process allows for a slower release of estradiol into the bloodstream, resulting in a prolonged and stable therapeutic effect. This characteristic makes it an invaluable component in long-acting injectable formulations. The compound typically appears as a white or almost white crystalline powder, which is practically insoluble in water but soluble in organic solvents like alcohol and acetone. Its structure and properties are meticulously controlled during our manufacturing process to ensure consistency and reliability.

Mechanism of Action and Pharmacokinetics
Upon administration, typically via intramuscular injection, Estradiol 17-Enanthate forms a depot in the muscle tissue. From this depot, it is slowly released and hydrolyzed by esterase enzymes in the body into 17β-estradiol and heptanoic acid. The released estradiol is identical to the hormone naturally produced by the human ovaries. It then binds to estrogen receptors (ERs), specifically ERα and ERβ, which are located in various tissues throughout the body, including the reproductive tract, bones, cardiovascular system, and central nervous system. This binding initiates a cascade of genomic effects that modulate gene expression, leading to the wide-ranging physiological responses associated with estrogen. The extended duration of action, often lasting for several weeks, reduces the frequency of administration, thereby improving patient compliance and convenience.

Therapeutic Applications and Importance
The primary application of Estradiol 17-Enanthate is in hormone replacement therapy (HRT) for managing symptoms associated with menopause. These symptoms can include hot flashes, vaginal atrophy, and osteoporosis. By supplementing the body's declining estrogen levels, it effectively alleviates these conditions and helps in the prevention of postmenopausal bone loss.

Furthermore, Estradiol 17-Enanthate is a critical component in combined injectable contraceptives. When used in combination with a progestin, such as norethisterone enanthate or algestone acetophenide, it provides a highly effective and reversible method of birth control. The estrogenic component helps regulate the menstrual cycle and enhances the contraceptive efficacy of the progestin.

Beyond these common uses, it is also utilized in the treatment of certain hormone-dependent cancers, such as prostate cancer and breast cancer, under specific therapeutic protocols. Its ability to provide sustained estrogen levels makes it a versatile tool in modern endocrinology and oncology.

The Unwavering Commitment to 99% Purity
In the pharmaceutical industry, purity is not just a benchmark—it's a prerequisite for safety and efficacy. At NINGBO INNO PHARMCHEM CO.,LTD., we guarantee a minimum purity of 99% for our Estradiol 17-Enanthate powder. Impurities in active pharmaceutical ingredients (APIs) or their intermediates can lead to adverse side effects, reduced therapeutic activity, or unpredictable outcomes. Our state-of-the-art manufacturing facilities and rigorous quality control protocols ensure that our product is free from contaminants and by-products. Each batch undergoes comprehensive testing using advanced analytical techniques like High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC) to verify its purity, identity, and compliance with international pharmacopeial standards. This meticulous attention to detail ensures that our clients receive a product they can trust for their critical applications.

Source from a Trusted Partner
As a premier manufacturer and supplier of Estradiol 17-Enanthate, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable partner in your supply chain. We understand the importance of a consistent and dependable supply of high-quality pharmaceutical intermediates. Our production capacity and streamlined logistics network ensure that we can meet demands of any scale, with secure and prompt delivery worldwide. If you are looking to buy Estradiol 17-Enanthate powder, we offer competitive price points without compromising on quality. We invite you to purchase from a company that prioritizes product excellence and customer satisfaction. Contact us to learn more about our product specifications, request a sample, or discuss your sourcing needs. Partner with us for unparalleled quality and service in the pharmaceutical chemical industry.