In the evolving landscape of animal health, effective antimicrobial solutions are crucial for maintaining livestock and aquatic animal welfare. Florfenicol (CAS 73231-34-2) stands as a cornerstone in veterinary medicine, renowned for its broad-spectrum antibacterial activity and safety profile. As a fluorinated synthetic analog of thiamphenicol, Florfenicol offers a robust defense against a wide array of bacterial pathogens that threaten animal populations globally.

Produced with meticulous attention to quality and purity, Florfenicol operates by inhibiting bacterial protein synthesis. It achieves this by binding to the 70S ribosomal 50S subunits of susceptible bacteria, thereby preventing the transfer of amino acids to extending peptide chains and halting subsequent protein formation. This precise mechanism of action makes it highly effective against both Gram-negative and Gram-positive organisms. A significant advantage of Florfenicol over its older counterparts, such as chloramphenicol, is its safety profile; Florfenicol does not carry the risk of inducing human aplastic anemia, making it a preferred choice in many veterinary applications. Furthermore, its unique molecular structure, featuring a fluorine atom at the C-3 position, provides enhanced stability against deactivation by certain bacterial enzymes, allowing it to maintain efficacy even against some chloramphenicol-resistant strains.

The versatility of Florfenicol extends across various animal species, addressing critical health challenges. In cattle, it is widely indicated for the treatment of bovine respiratory disease (BRD), a common and economically significant ailment caused by pathogens like Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. Beyond respiratory infections, Florfenicol is also effective in treating bovine interdigital phlegmon, commonly known as foot rot, which is associated with bacteria such as Fusobacterium necrophorum and Prevotella melaninogenica. Its rapid onset of action and prolonged inhibitory effects contribute to fewer re-treatments and improved recovery rates.

For swine, Florfenicol is indispensable for controlling respiratory infections caused by a spectrum of bacteria, including Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Glaesserella parasuis, Pasteurella multocida, and Streptococcus suis. Its efficacy helps in reducing morbidity and mortality, thereby safeguarding herd health and productivity. The application of Florfenicol also extends prominently into aquaculture, where it is approved for controlling mortality due to enteric septicemia in catfish, furunculosis in freshwater-reared salmonids (associated with Aeromonas salmonicida), coldwater disease (caused by Flavobacterium psychrophilum), columnaris disease (linked to Flavobacterium columnare) in freshwater-reared finfish, and streptococcal septicemia (due to Streptococcus iniae) in warmwater finfish. This broad utility underscores its importance in preventing and treating a range of aquatic diseases.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing Florfenicol raw materials of exceptional purity, consistently exceeding 99%. Our products adhere strictly to international pharmaceutical standards, including GMP, ISO 9001, USP, and BP, ensuring consistent quality and reliability. We understand the critical need for dependable and safe veterinary pharmaceutical ingredients, and our production processes are designed to meet the highest industry benchmarks. For those seeking to purchase high-grade Florfenicol, whether as a raw material or for further formulation, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer and supplier. We offer competitive price options for bulk orders and prioritize safe, efficient global delivery. Partner with us to enhance your animal health product lines with a superior quality antibiotic.