Medetomidine Hydrochloride (HCl), identified by its CAS No. 86347-15-1, is a highly effective pharmaceutical compound widely recognized for its potent sedative and analgesic properties. As a leading manufacturer and supplier of high-quality pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. offers Medetomidine HCl powder with a purity exceeding 99%. This exceptional purity ensures optimal efficacy and safety for its intended professional applications across the globe. Our commitment to rigorous quality control makes us a trusted source for this essential compound.

At its core, Medetomidine HCl functions as a selective alpha-2 adrenergic receptor agonist. This mechanism of action allows it to exert profound central nervous system depression, leading to its characteristic sedative and analgesic effects. It achieves this by decreasing the release of norepinephrine from presynaptic nerve terminals. The compound is a racemic mixture, with dexmedetomidine being the pharmacologically active stereoisomer responsible for its therapeutic benefits. This precise interaction ensures effective restraint and pain relief, crucial for various medical procedures.

In veterinary medicine, Medetomidine HCl is indispensable as a sedative and analgesic. It is primarily used to facilitate clinical examinations, minor surgical procedures, and various diagnostic processes in both dogs and cats. Often employed as a pre-anesthetic agent, it can be combined with other compounds such as opioids (e.g., butorphanol, buprenorphine) or dissociative anesthetics (e.g., ketamine) to achieve comprehensive general anesthesia for short periods. Its ability to produce significant muscle relaxation makes it particularly useful for managing fractious or anxious animals, ensuring their comfort and the safety of veterinary personnel during procedures.

While highly effective, the use of Medetomidine HCl requires careful consideration. It is generally recommended for use in clinically healthy animals (ASA classes I and II) due to its pronounced cardiovascular effects, which can include peripheral vasoconstriction and bradycardia. Veterinarians must monitor animals closely for changes in heart rate, blood pressure, respiratory rate, and body temperature during sedation. The drug is contraindicated in animals with pre-existing cardiac disease, respiratory disorders, liver or kidney diseases, or those in shock or severely debilitated. Proper dosage, administered intravenously (IV) or intramuscularly (IM), is critical, with IV administration often leading to a more rapid onset of effect.

Beyond its well-established role in veterinary pharmacology, Medetomidine also finds a unique application in industrial settings. The free base form of Medetomidine has been successfully utilized as an active ingredient in marine paints, specifically as an antifouling substance. Marketed under names like Selektope, it helps prevent the attachment and growth of marine organisms, such as barnacles, on ship hulls and other submerged structures. This highlights the versatility and broad utility of this chemical compound in various specialized fields.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to maintaining the highest standards in the production and distribution of Medetomidine HCl. Our advanced chemical production facilities and professional research and development team ensure that our products consistently meet or exceed global pharmaceutical standards, including USP and BP. We implement stringent quality control measures at every stage, from raw material sourcing to final product packaging, guaranteeing a minimum purity of 99%. Clients can confidently buy from us, knowing they receive a product of superior quality.

As a reputable manufacturer and global supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers secure and efficient worldwide shipping for Medetomidine HCl powder. We understand the critical importance of reliable delivery for pharmaceutical products and employ various secure methods to ensure packages arrive safely within 12-15 days to numerous countries. For detailed price information, minimum order quantities, or to purchase Medetomidine HCl, interested parties are encouraged to contact our sales team. We offer flexible payment options and are committed to long-term partnerships with our clients, providing consistent supply and expert support.