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High Purity N,N'-Diisopropylcarbodiimide (DIC) CAS 693-13-0 for Synthesis

N,N'-Diisopropylcarbodiimide (DIC), identified by its CAS number 693-13-0, stands as a pivotal reagent in the landscape of organic chemistry. NINGBO INNO PHARMCHEM CO.,LTD., a dedicated supplier of chemical intermediates, provides high-quality DIC for various industrial and research applications.

This compound, with the chemical formula C7H14N2, presents as a clear, colorless to slightly yellow liquid at standard room temperature. It possesses distinct physical characteristics, including a boiling point typically ranging from 145 to 148 degrees Celsius (at atmospheric pressure) and a density around 0.815 g/mL at 20 degrees Celsius. While insoluble in water, DIC exhibits good solubility in common organic solvents such as benzene, ethanol, and ether, facilitating its use in diverse reaction environments.

The primary utility of N,N'-Diisopropylcarbodiimide lies in its potent dehydrating capabilities. It is widely employed as a dehydrating agent in the synthesis of complex molecules, including crucial pharmaceuticals like amikacin and vital biological compounds like glutathione. Beyond dehydration, DIC is instrumental in the formation of various functional groups and intermediates. It plays a significant role in the synthesis of acid anhydrides, aldehydes, ketones, and isocyanates, showcasing its versatility as a chemical building block.

Perhaps one of the most celebrated applications of N,N'-Diisopropylcarbodiimide is in peptide synthesis. Acting as a powerful coupling agent, DIC efficiently promotes the formation of amide bonds between compounds possessing free carboxyl groups and free amino groups. A key advantage of using DIC in peptide synthesis is its ability to facilitate these reactions rapidly at room temperature, simplifying procedures and reducing energy requirements. The reaction mechanism involves the formation of an activated intermediate that readily couples with the amino component. The byproduct of this coupling reaction is dicyclohexyl urea, which can typically be separated from the desired product.

Given its efficacy and versatility, N,N'-Diisopropylcarbodiimide finds extensive application across numerous fields. Its use is prevalent in the pharmaceutical industry for synthesizing active drug ingredients, in the health products sector, and in the cosmetics industry. Furthermore, it is indispensable in the production of biological preparations and serves as a fundamental reagent in general organic synthesis laboratories worldwide. Its ability to drive condensation reactions under mild conditions makes it a preferred choice for sensitive substrates.

NINGBO INNO PHARMCHEM CO.,LTD. understands the critical need for high-purity reagents in these demanding applications. Our N,N'-Diisopropylcarbodiimide is typically supplied with a minimum assay of 99%, ensuring reliable and consistent results in downstream processes. We offer flexible packaging options, including standard drum sizes like 25kg, to accommodate various customer needs, from laboratory scale to larger industrial production. Minimum Order Quantity (MOQ) can often be as low as 1kg for testing purposes, though bulk purchase options starting from 100kg are also readily available.

As a trusted manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing competitive price structures for N,N'-Diisopropylcarbodiimide. Prospective customers seeking to buy this high-quality intermediate can easily inquire about specific price details, lead times, and shipping options. We encourage those looking to purchase N,N'-Diisopropylcarbodiimide to contact us directly to discuss their requirements and secure a reliable supply. We aim to be your preferred partner for essential chemical raw materials, offering seamless procurement and dependable product quality.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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