Octreotide is a synthetic cyclic octapeptide analog of the naturally occurring hormone somatostatin. As a crucial active pharmaceutical ingredient (API), it plays a significant role in the treatment of various medical conditions, particularly those involving the excessive secretion of growth hormone and other peptides. Obtaining high purity Octreotide Powder is paramount for pharmaceutical manufacturers and research laboratories, ensuring the efficacy, safety, and consistency of downstream drug products and studies.

The physical form of Octreotide as a high purity powder is essential for its handling, storage, and incorporation into various formulations. Key specifications define the quality of this raw material. Typically appearing as a white or off-white powder, high-grade Octreotide is known for its very good solubility in water and acetic acid, properties critical for its formulation into injectable solutions. The molecular formula is C51H70N10O12S2, with a molecular weight of approximately 1079.3. Standard quality control parameters include a specific optical rotation, a defined pH range (usually between 5.0 and 7.0), and limits on water content, often not exceeding 4.0% to ensure stability.

Detailed analytical testing confirms the identity and purity of Octreotide Powder. Amino acid analysis verifies the correct peptide sequence and composition. Related substances testing is critical for identifying and quantifying any impurities or related peptides that may arise during synthesis or storage. Strict limits are typically set for both individual unspecified impurities and the total impurity level (e.g., NMT 0.5% for each unspecified impurity and NMT 2.0% total impurity). The assay, which measures the actual percentage of Octreotide in the sample, is a direct indicator of purity and potency. High-quality material should meet pharmacopoeial standards, often showing an assay result within the range of 95.0% to 105.0%.

Additional analytical techniques such as Mass Spectrometry (MS) are used to confirm the molecular weight and structure, providing further assurance of identity and purity. The content of residual solvents, such as acetic acid (as mentioned in the source material, potentially up to 12.0%), is also monitored to ensure compliance with regulatory guidelines and product stability.

The applications of Octreotide in medicine are well-established. It is primarily used to manage symptoms associated with neuroendocrine tumors (NETs), including carcinoid tumors and VIPomas, which secrete excessive amounts of hormones causing conditions like severe diarrhea and flushing. Octreotide effectively suppresses the release of these hormones. It is also a cornerstone therapy for acromegaly, a disorder caused by excessive growth hormone production, by inhibiting growth hormone release from the pituitary gland. In some cases, it is used in the management of bleeding from esophageal varices.

The effectiveness and safety of Octreotide-based drug products are directly dependent on the quality and purity of the API used in their manufacture. Impurities can affect stability, lead to adverse reactions, or reduce potency. Therefore, sourcing Octreotide Powder from a reliable supplier committed to stringent quality control is non-negotiable for pharmaceutical companies and researchers.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high purity Octreotide Powder that meets the demanding requirements of the pharmaceutical industry and research sector. We understand the critical nature of APIs and ensure that our Octreotide Powder adheres to rigorous quality standards, including compliance with major pharmacopoeias such as USP, BP, and EP where applicable. Our commitment to quality is reflected in thorough testing protocols that confirm identity, purity, potency, and the absence of harmful impurities.

The supply chain integrity and proper handling are also vital. High purity Octreotide Powder requires specific storage conditions, typically in a cool, dry place, to maintain its stability and prevent degradation. Packaging in appropriate containers, such as sealed drums, is essential for protecting the material during transport and storage. NINGBO INNO PHARMCHEM CO.,LTD. ensures that these requirements are met throughout the supply process.

Choosing NINGBO INNO PHARMCHEM CO.,LTD. as your supplier means partnering with a company that prioritizes quality, reliability, and customer service. We facilitate the acquisition of high-grade pharmaceutical raw materials essential for drug development and manufacturing. For those looking to buy or purchase Octreotide Powder, we offer competitive price options and a streamlined procurement process. As a trusted partner, we work closely with reputable sources, ensuring that the Octreotide Powder we supply originates from reliable manufacturers who adhere to Good Manufacturing Practices (GMP).

Our goal is to be the go-to supplier for laboratories and pharmaceutical companies requiring Octreotide Powder for their critical work. We aim to simplify the purchase experience while guaranteeing the quality necessary for regulatory compliance and successful product outcomes. Contact NINGBO INNO PHARMCHEM CO.,LTD. to discuss your requirements and learn more about our high purity Octreotide Powder.