Povidone Iodine, chemically represented as a stable complex of polyvinylpyrrolidone (PVP) and iodine, is a widely recognized and highly effective broad-spectrum antiseptic. This pharmaceutical raw material, identified by its CAS number 25655-41-8, is indispensable in various medical and healthcare applications. It functions by releasing iodine, which rapidly oxidizes vital components of microbial cells, including bacteria, viruses, fungi, and protozoa, leading to their swift inactivation. Its efficacy across such a wide range of pathogens makes it a cornerstone in infection prevention and control.

The demand for high-quality Povidone Iodine powder stems directly from its critical use in preparing topical antiseptics, disinfectants, and surgical scrubs. Unlike elemental iodine, the complex form with PVP enhances solubility in water and significantly reduces irritation and toxicity, making it safer for repeated human use while maintaining potent germicidal activity. This characteristic balance of efficacy and reduced side effects underscores its preference in clinical settings worldwide.

Our offering is a premium-grade Povidone Iodine powder, meticulously manufactured to meet the stringent requirements of pharmaceutical applications. As a raw material, its quality directly impacts the safety and efficacy of the final drug products or antiseptic solutions. Therefore, selecting a source that adheres to rigorous quality control measures is paramount. The powder form allows for versatile formulation into various dosage forms, including solutions, ointments, sprays, and surgical scrubs, catering to diverse medical needs.

Key quality attributes of pharmaceutical-grade Povidone Iodine powder include its appearance as a white or off-white solid, its solubility characteristics in various solvents, and critical parameters such as assay percentage, water content, heavy metals content, and levels of related substances or impurities. Meeting pharmacopoeial standards such as USP, EP, and BP is not just a regulatory requirement but a fundamental indicator of product quality and consistency, ensuring the material is safe and effective for its intended use in medicinal products.

The applications of Povidone Iodine powder are extensive within the medical field. It is widely used for disinfecting skin and mucous membranes before surgical procedures or injections. It is also a primary component in formulations for treating and preventing infections in wounds, burns, cuts, and abrasions. In hospital settings, Povidone Iodine-based solutions are essential for hand hygiene and disinfecting medical equipment. Its reliability and broad-spectrum activity make it a trusted antiseptic choice for both professional healthcare providers and consumer health products.

Ensuring the supply chain integrity and the consistent quality of pharmaceutical raw materials like Povidone Iodine powder requires sophisticated manufacturing processes and robust quality assurance systems. Each batch must undergo thorough testing to verify its compliance with specified purity and potency standards. Factors such as particle size distribution can also be critical for certain formulations, influencing dissolution rates and homogeneity of the final product. Proper storage conditions, typically in tight, light-resistant containers in a cool place, are also vital to maintain the stability and efficacy of the powder over time.

The mechanism by which Povidone Iodine exerts its antimicrobial effect involves the gradual release of free iodine from the complex. This free iodine then interacts with essential macromolecules in microbial cells, including proteins and nucleic acids, disrupting their structure and function. This non-specific mode of action makes the development of microbial resistance highly unlikely, which is a significant advantage in an era of increasing antibiotic resistance. The staining properties of Povidone Iodine, while sometimes seen as a minor drawback, also serve as a visual indicator of the disinfected area.

The global pharmaceutical industry relies heavily on dependable sources for critical raw materials. The availability of high-purity Povidone Iodine powder that consistently meets international quality standards is crucial for the continuous production of essential antiseptic and disinfectant products used in hospitals, clinics, and homes worldwide. The manufacturing process for Povidone Iodine involves the polymerization of N-vinyl-2-pyrrolidone and subsequent complexation with iodine. Controlling the molecular weight distribution of the PVP component and the ratio of iodine to PVP in the complex are critical steps influencing the properties and stability of the final product.

Adherence to Good Manufacturing Practices (GMP) is fundamental in the production of pharmaceutical raw materials. A GMP-compliant facility ensures that products are consistently produced and controlled according to quality standards. This covers all aspects from the starting materials, premises, and equipment to the training and personal hygiene of staff. Maintaining comprehensive documentation for every stage of the process provides traceability and accountability, reinforcing the commitment to quality and safety that is expected in the pharmaceutical supply chain.

Our Povidone Iodine powder is characterized by its uniform appearance and consistent performance, attributes that are essential for ease of formulation and reliable product quality in downstream manufacturing. Parameters such as melting point range and residue on ignition are also monitored to ensure the chemical integrity and purity of the compound. The low levels of heavy metals and other impurities are particularly important for materials intended for topical application or use on mucous membranes, minimizing the risk of adverse reactions.

Understanding the solubility profile of Povidone Iodine powder is also crucial for formulators. While readily soluble in aqueous solutions, its behavior in organic solvents can vary, influencing the choice of co-solvents or formulation techniques for non-aqueous preparations or specific delivery systems. The stability of the complex is influenced by factors such as pH, temperature, and light exposure, necessitating appropriate packaging and storage conditions to preserve its potency throughout its shelf life.

When seeking a reliable manufacturer or supplier of Povidone Iodine powder CAS 25655-41-8, partnering with a company that demonstrates a deep understanding of pharmaceutical quality requirements and a commitment to consistent supply is key. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality pharmaceutical raw materials, including Povidone Iodine powder, backed by robust quality control and technical support.

For detailed information regarding price, availability, and specifications, or to learn how to buy or purchase Povidone Iodine powder from a trusted supplier, please reach out to us. We are committed to supporting your manufacturing needs with competitive pricing and reliable delivery, ensuring you receive a pharmaceutical-grade product that meets the highest industry standards. Contact NINGBO INNO PHARMCHEM CO.,LTD. today to discuss your requirements and explore how we can be your preferred manufacturer and supplier for Povidone Iodine and other pharmaceutical raw materials.