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High-Purity Rimegepant Intermediate Dihydrochloride (CAS 1373116-07-4)

NINGBO INNO PHARMCHEM CO.,LTD. is proud to present (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol Dihydrochloride, a vital pharmaceutical intermediate with CAS No. 1373116-07-4. This complex chemical entity is indispensable in the synthesis of advanced therapeutic agents, particularly serving as a key precursor for Rimegepant Sulfate. As the pharmaceutical industry continues to innovate, the demand for high-quality, reliable intermediates becomes paramount. Our commitment is to meet this demand with products that adhere to the strictest global standards of quality and purity.


Rimegepant, for which this dihydrochloride serves as an essential building block, represents a significant breakthrough in the treatment of migraines. It stands out as a pioneering oral calcitonin gene-related peptide (CGRP) receptor antagonist, unique in its ability to both treat acute migraine attacks and prevent future episodes. The precision and integrity of intermediates like (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol Dihydrochloride are crucial for ensuring the efficacy and safety of the final drug product. Our product boasts a molecular formula of C16H18Cl2F2N2O and a molecular weight of approximately 363.23. It typically appears as a white to yellow powder, and for optimal stability, it is recommended to store it at 2-8°C under refrigerated conditions.


At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the foundation of any successful pharmaceutical product lies in the quality of its raw materials. Our manufacturing processes for (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol Dihydrochloride are rigorously controlled, ensuring a consistently high purity level, typically not less than 98.0%. This superior quality makes it an ideal choice for pharmaceutical research, development, and large-scale synthesis. Beyond its primary role in Rimegepant production, this compound is also recognized as Rimegepant 2HCL, Rimegepant Impurity 26, or a Rimegepant intermediate, highlighting its multifaceted utility in pharmaceutical standards and fine chemical applications. Its precise stereochemistry, indicated by the (5S,6S,9R) designation, is critical for achieving the desired pharmacological activity of the final Rimegepant API.


As a leading manufacturer and reliable supplier of high-quality pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is well-equipped to meet the diverse needs of the global pharmaceutical market. We maintain robust production capabilities and a commitment to efficient logistics, ensuring timely delivery to our clients worldwide. For those looking to buy or purchase (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol Dihydrochloride, we offer competitive price structures tailored to bulk orders and specific project requirements. Our dedicated sales team is ready to provide detailed product specifications, certificates of analysis, and respond to all inquiries regarding quantities, lead times, and custom synthesis needs. Partner with us for your pharmaceutical intermediate requirements and experience the assurance of quality, reliability, and excellent service.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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