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High-Purity Sulfathiazole Sodium (CAS 144-74-1) for Pharmaceutical Use

Sulfathiazole Sodium, identified by its Chemical Abstracts Service (CAS) number 144-74-1, stands as a pivotal active pharmaceutical ingredient (API) in the realm of antimicrobial medicine. As a distinguished sulfonamide antibiotic, this compound has been extensively utilized for its potent bacteriostatic properties. NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer high-quality Sulfathiazole Sodium, meeting stringent industry standards for pharmaceutical and veterinary applications.


Chemically known as 4-amino-N-2-thiazolyl-benzenesulfonamide monosodium salt, Sulfathiazole Sodium typically presents as a white or almost white crystalline powder, sometimes appearing as colorless or yellowish fine crystalline powder or granules. Its molecular formula is C9H8N3NaO2S2·1 1/2 H2O, and it is notably easily soluble in water and ethanol, forming an alkaline aqueous solution. This solubility profile facilitates its formulation into various pharmaceutical products, making it a versatile ingredient for diverse applications.


The efficacy of Sulfathiazole Sodium stems from its well-understood mechanism of action. It functions as a competitive inhibitor of para-aminobenzoic acid (PABA), a crucial substrate for the bacterial enzyme dihydropteroate synthase. By interfering with the synthesis of dihydrofolic acid, a vital precursor to essential nucleic acids and proteins, Sulfathiazole Sodium effectively inhibits bacterial growth and replication. This makes it a powerful bacteriostatic agent, preventing the proliferation of harmful microorganisms.


Historically, Sulfathiazole Sodium has been instrumental in combating a wide array of bacterial infections. Its broad spectrum of activity targets both Gram-positive and Gram-negative bacteria, including common pathogens such as Staphylococcus, Streptococcus, and Pneumococcus. It has found application in treating conditions like meningitis, hemolytic streptococcus infections, and certain gram-negative bacillus infections. While its systemic use has seen a decline due to the advent of newer antibiotics, it remains a valuable component in topical preparations, often combined with other sulfonamides, for addressing localized skin and vaginal infections. Furthermore, Sulfathiazole Sodium continues to be a significant compound in veterinary research and medicine, particularly in inhibiting folate formation by gut bacteria in animal models and in in-vitro microbiological susceptibility testing to determine antibiotic effectiveness.


At NINGBO INNO PHARMCHEM CO.,LTD., we prioritize the quality and purity of our products. Our Sulfathiazole Sodium consistently meets the highest purity standards, with typical assays exceeding 99%. Our commitment to stringent quality control measures and adherence to Good Manufacturing Practices (GMP) ensure a product that is reliable, consistent, and safe for its intended applications. Each batch undergoes rigorous testing to guarantee its efficacy and compliance with industry specifications.


For optimal preservation of its integrity and potency, Sulfathiazole Sodium should be stored in a cool, dry place, protected from direct light, in tightly sealed containers. We invite interested parties to consider NINGBO INNO PHARMCHEM CO.,LTD. as your trusted manufacturer and supplier for high-quality Sulfathiazole Sodium. For detailed price information or to buy this essential API, please reach out to our dedicated sales team. We offer competitive pricing and flexible options for purchase to meet diverse requirements globally, ensuring a seamless procurement process for our valued clients.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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