NINGBO INNO PHARMCHEM CO.,LTD. is pleased to announce the availability of its high-quality Venetoclax Intermediate, specifically the compound identified by CAS Number 1228780-72-0.

Venetoclax, a groundbreaking selective inhibitor of the BCL-2 protein, has revolutionized the treatment landscape for certain types of leukemia, including chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). Its mechanism of action, which targets the BCL-2 protein responsible for keeping cancer cells alive, makes it a vital component in modern oncology therapy. The successful synthesis and large-scale production of Venetoclax rely heavily on the availability of high-quality, well-characterized intermediates at each step of the manufacturing process. Recognizing this critical need, NINGBO INNO PHARMCHEM CO.,LTD. has prioritized the development and supply of key intermediates to support global pharmaceutical manufacturers.

The compound 1-((2-(4-Chlorophenyl)-4,4-Dimethylcyclohex-1-Enyl)Methyl) Piperazine, CAS 1228780-72-0, is a crucial building block in the complex synthesis pathway of Venetoclax API. Its chemical structure, involving a piperazine ring attached via a methylene group to a substituted cyclohexene bearing a 4-chlorophenyl group, is essential for forming the final active pharmaceutical ingredient. The purity and structural integrity of this intermediate directly impact the yield, purity, and overall quality of the final Venetoclax product. Therefore, sourcing this intermediate from a reliable and quality-conscious supplier is paramount for pharmaceutical companies.

NINGBO INNO PHARMCHEM CO.,LTD.'s offering of CAS 1228780-72-0 meets stringent quality standards. The product is supplied as a white powder, a common and stable physical form for handling and storage in pharmaceutical manufacturing environments. Analytical data confirms a purity of greater than 98%, ensuring minimal impurities that could interfere with subsequent synthesis steps or contaminate the final API. The molecular formula is C19H27ClN2, with a molecular weight of 318.88, values consistent with the compound's established structure.

Furthermore, predicted physical properties such as a boiling point of 421.2±45.0 °C, a density of 1.072±0.06 g/cm3, and a pKa of 9.21±0.10 provide valuable information for process development and optimization during Venetoclax synthesis. While these are predicted values, they offer insights into the compound's behavior under various conditions, aiding chemists and engineers in designing efficient and scalable synthesis routes.

The availability of high-purity intermediates like CAS 1228780-72-0 from a trusted manufacturer is a significant factor in ensuring a stable and cost-effective supply chain for Venetoclax production. As the demand for Venetoclax continues to grow due to its clinical success, the need for consistent, high-quality raw materials intensifies. NINGBO INNO PHARMCHEM CO.,LTD. understands the critical nature of this supply chain and is committed to providing intermediates that meet the rigorous requirements of the pharmaceutical industry.

Our commitment extends beyond simply supplying the chemical; it involves understanding the needs of our clients in the pharmaceutical sector. We recognize that the quality of the intermediate is not just a technical specification but a direct contributor to patient safety and therapeutic efficacy. Therefore, our manufacturing processes adhere to strict quality control protocols, ensuring batch-to-batch consistency and reliability.

For pharmaceutical companies engaged in the synthesis of Venetoclax, securing a dependable source for key intermediates like CAS 1228780-72-0 is a strategic decision. NINGBO INNO PHARMCHEM CO.,LTD. stands ready to be that partner, offering this essential intermediate in quantities suitable for laboratory research, process development, and large-scale commercial production. The minimum order quantity (MOQ) starts from 1 kg, facilitating access for various project sizes.

Pharmaceutical manufacturers and researchers seeking a reliable supply of high-purity Venetoclax Intermediate CAS 1228780-72-0 are encouraged to explore the offering from NINGBO INNO PHARMCHEM CO.,LTD. Our position as a dedicated manufacturer and supplier of pharmaceutical intermediates allows us to offer competitive price and assured quality.

To buy or purchase this essential intermediate, or to inquire about bulk quantities and specifications, potential clients are invited to contact NINGBO INNO PHARMCHEM CO.,LTD. directly. We are committed to supporting the advancement of life-saving therapies by providing the foundational chemical building blocks required for their creation. Choose NINGBO INNO PHARMCHEM CO.,LTD. for your Venetoclax intermediate needs and benefit from a partnership focused on quality, reliability, and excellence in pharmaceutical chemical supply. We aim to be your preferred supplier and manufacturer for Venetoclax intermediates, facilitating the seamless production of this vital API.