Adenosine, identified by CAS number 58-61-7, is a naturally occurring nucleoside composed of adenine attached to a ribose sugar molecule. It plays a pivotal and multifaceted role in biochemistry and cellular function across various biological systems. As a fine, white powder, it is a critical raw material used in numerous research and pharmaceutical applications. Its significance stems from its involvement in key biological processes, acting primarily as a signaling molecule and a fundamental component of energy-carrying molecules like ATP, ADP, and AMP.

One of the primary functions of adenosine involves cell signal transduction regulation. Adenosine exerts its effects by binding to specific cell surface receptors, namely the A1, A2a, A2b, and A3 receptors, which are G protein-coupled receptors. The activation of these receptors triggers intracellular signaling cascades that modulate a wide range of cellular activities. For instance, stimulation of A1 and A3 receptors typically inhibits adenylyl cyclase activity, decreasing intracellular cAMP levels, while activation of A2a and A2b receptors generally stimulates adenylyl cyclase, increasing cAMP. Through these mechanisms, adenosine can influence neurotransmission, inflammation, smooth muscle tone, and cardiovascular function. Notably, its interaction with receptors can lead to anti-inflammatory and immunosuppressive effects, making it a subject of interest in research for inflammatory conditions.

Adenosine also plays a crucial part in energy metabolism regulation. It is an integral part of adenosine triphosphate (ATP), the primary energy currency of the cell. During periods of high metabolic activity or stress, such as hypoxia or ischemia, ATP is broken down, leading to an increase in extracellular adenosine concentrations. This surge in adenosine acts as a signal of metabolic distress. By binding to its receptors, adenosine can initiate protective responses. For example, in the cardiovascular system, it can cause vasodilation, increasing blood flow and oxygen delivery to tissues. In the brain, it can reduce neuronal activity, conserving energy. Thus, adenosine acts as a critical feedback mechanism, helping to match energy supply with demand and protecting cells from damage under adverse metabolic conditions.

Furthermore, adenosine is known for its effects on nerve inhibition. In the central nervous system, adenosine acts as a neuromodulator, primarily through its inhibitory effects mediated by A1 receptors. It can decrease the release of excitatory neurotransmitters like glutamate and acetylcholine, thereby reducing neuronal excitability. This inhibitory action contributes to adenosine's roles in promoting sleep, reducing anxiety, and potentially exerting analgesic effects. The sedative and hypnotic properties of adenosine agonists have been explored, and its role in regulating sleep-wake cycles is well-established. In clinical settings, the ability of adenosine to transiently block atrioventricular nodal conduction is utilized in the treatment of certain supraventricular tachycardias, highlighting its significant pharmacological utility.

As a raw material, the quality of Adenosine Powder is paramount for its intended applications, particularly in the pharmaceutical industry. High-quality material typically meets stringent purity standards, often exceeding 99%. Specifications commonly include tests for appearance (white powder), particle size, odor, taste, loss on drying, residue on ignition, residual solvents, heavy metals, and microbial limits (Total Plate Count, Yeast & Mold, E. coli, Salmonella). Compliance with pharmacopoeial standards such as USP or BP, along with quality management certifications like ISO 9001 and GMP, are indicators of a reliable product suitable for demanding uses.

The production and supply of Adenosine Powder require careful control over the manufacturing process to ensure consistency and purity. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality Adenosine Powder, adhering to strict quality control protocols at every stage. Our product is a fine white powder with a purity typically above 99%, suitable for various applications requiring a high standard of quality.

Researchers and manufacturers seeking a dependable manufacturer and supplier of Adenosine Powder (CAS 58-61-7) can consider NINGBO INNO PHARMCHEM CO.,LTD. Our commitment to quality ensures that the product meets the required specifications for diverse research and pharmaceutical purposes. For information regarding the current price of Adenosine Powder, potential bulk order discounts, or details on how to buy or purchase this product, please contact NINGBO INNO PHARMCHEM CO.,LTD. directly. We offer flexible packaging options and aim for efficient logistics to meet the global demand for this essential nucleoside. Obtaining competitive pricing and securing a reliable source for Adenosine Powder is crucial for continuous production and research, and NINGBO INNO PHARMCHEM CO.,LTD. is positioned to fulfill these requirements as a trusted global supplier.