Teneligliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor widely prescribed for the management of type 2 diabetes mellitus. Its mechanism involves enhancing incretin hormone levels, which helps regulate blood glucose. The availability of a high-quality intermediate like CAS 401566-79-8 is therefore essential for the consistent and reliable production of this important therapeutic agent.

Chemically, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine has the molecular formula C14H18N4. It typically presents as a white to off-white crystalline powder. This physical form is advantageous for various processing steps in pharmaceutical manufacturing, including handling, purification, and analysis. The quality of this intermediate directly impacts the yield, purity, and overall characteristics of the final Teneligliptin API (Active Pharmaceutical Ingredient).

Manufacturing of pharmaceutical intermediates must adhere to stringent quality control measures and regulatory standards to ensure the safety and efficacy of the final drug product. Compliance with internationally recognized standards such as ISO 9001 and pharmaceutical-specific guidelines like GMP (Good Manufacturing Practices) is paramount. These frameworks cover various aspects, from raw material sourcing and production processes to quality assurance, testing, and documentation, including Certificates of Analysis (COA), Material Safety Data Sheets (MSDS), and detailed specifications.

A reputable manufacturer emphasizes rigorous testing to confirm the purity, identity, and other critical attributes of CAS 401566-79-8. Purity levels, typically exceeding 98%, are crucial to minimize impurities that could carry through to the final API or affect synthesis efficiency. Storage conditions, such as being sealed and kept in a cool, dry environment, are also important to maintain product stability over time.

Investing in research and development is key for continuous improvement in the synthesis of intermediates. Optimization of reaction conditions, exploration of alternative synthetic routes, and improvement of purification methods contribute to enhanced product quality, reduced costs, and minimized environmental impact. The ability to customize specifications or provide technical documentation further supports clients' specific needs and regulatory requirements.

Reliable supply chain management, including professional and efficient shipping, is also a critical factor when sourcing pharmaceutical intermediates. Ensuring the material reaches the client safely and on time, with appropriate packaging options (e.g., 1 kg bags or 25 kg drums), facilitates seamless integration into their manufacturing schedule. Providing sample quantities for testing and allowing client audits of manufacturing facilities build trust and demonstrate commitment to quality.

Access to a dependable source of high-quality 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine (CAS 401566-79-8) is fundamental for companies involved in the production of Teneligliptin. For those seeking a reliable manufacturer or supplier of this essential intermediate, inquiries are welcome. Information regarding current price, minimum order quantity, and how to buy or purchase this product is readily available upon request. Securing a consistent supply of this high-purity powder is a crucial step in bringing effective diabetes treatments to market.